Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells.
about
Protein tyrosine phosphatases as wardens of STAT signalingInhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemiaPAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesisBCR-ABL affects STAT5A and STAT5B differentiallyGenomic quantitative real-time PCR proves residual disease positivity in more than 30% samples with negative mRNA-based qRT-PCR in Chronic Myeloid LeukemiaHematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling.Induction of apoptosis by directing oncogenic Bcr-Abl into the nucleus.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy.Src family kinases and their role in hematological malignancies.Effects of a Particular Heptapeptide on the IFN-α-Sensitive CML Cells.Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.
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Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
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2012年學術文章
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name
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@en
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@nl
type
label
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@en
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@nl
prefLabel
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@en
Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@nl
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Src family kinases mediate cyt ...... AT5 in BCR-ABL-positive cells.
@en
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D Fahrenkamp
G Müller-Newen
H Schmitz-Van de Leur
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P2888
P304
P356
10.1038/ONC.2012.369
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P577
2012-08-27T00:00:00Z
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1018729941