Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
about
The pathogenic implication of abnormal interaction between apolipoprotein E isoforms, amyloid-beta peptides, and sulfatides in Alzheimer's diseaseThe role and metabolism of sulfatide in the nervous systemEnzyme, cell and gene-based therapies for metachromatic leukodystrophyAdult CST-null mice maintain an increased number of oligodendrocytesGene therapy for metachromatic leukodystrophy.Sulfatide with short fatty acid dominates in astrocytes and neurons.Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix.Apolipoprotein E mediates sulfatide depletion in animal models of Alzheimer's diseaseChronic caloric restriction attenuates a loss of sulfatide content in PGC-1α-/- mouse cortex: a potential lipidomic role of PGC-1α in neurodegeneration.Sulfatides facilitate apolipoprotein E-mediated amyloid-beta peptide clearance through an endocytotic pathway.Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor.Sulfocerebrosides upregulate liposome uptake in human astrocytes without inducing a proinflammatory response.Comparative efficacy and safety of multiple routes of direct CNS administration of adeno-associated virus gene transfer vector serotype rh.10 expressing the human arylsulfatase A cDNA to nonhuman primates.Sulfatide is essential for the maintenance of CNS myelin and axon structure.Partial cure of established disease in an animal model of metachromatic leukodystrophy after intracerebral adeno-associated virus-mediated gene transfer.Embryonic stem cell-based reduction of central nervous system sulfatide storage in an animal model of metachromatic leukodystrophy.Layer-specific sulfatide localization in rat hippocampus middle molecular layer is revealed by nanoparticle-assisted laser desorption/ionization imaging mass spectrometry.Oligodendrocyte-specific ceramide galactosyltransferase (CGT) expression phenotypically rescues CGT-deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level.Toward a better understanding of brain lesions during metachromatic leukodystrophy evolution.Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes.Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy.
P2860
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P2860
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
@zh-my
2004年学术文章
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2004年學術文章
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2004年學術文章
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name
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@en
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@nl
type
label
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@en
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@nl
prefLabel
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@en
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@nl
P2093
P1476
Accumulation of sulfatide in neuronal and glial cells of arylsulfatase A deficient mice.
@en
P2093
Jan-Eric Månsson
Marie Molander-Melin
Pam Fredman
Sebastian Franken
Volkmar Gieselmann
Zarah Pernber
P304
P356
10.1023/B:NEUR.0000046572.53905.2C
P577
2004-07-01T00:00:00Z