Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation.
about
Ethanol effects on GABA-gated current in a model of increased alpha4betadelta GABAA receptor expression depend on time course and preexposure to low concentrations of the drug.Ethanol/naltrexone interactions at the mu-opioid receptor. CLSM/FCS study in live cells.Molecular targets and mechanisms for ethanol action in glycine receptorsGABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sitesA transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics.Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues.The role of GABA(A) receptors in the development of alcoholismNanoscale effects of ethanol and naltrexone on protein organization in the plasma membrane studied by photoactivated localization microscopy (PALM).Structural basis for alcohol modulation of a pentameric ligand-gated ion channelModulating inhibitory ligand-gated ion channels.Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activationEthanol reversal of cellular tolerance to morphine in rat locus coeruleus neuronsThe size of the unbranched aliphatic chain determines the immunomodulatory potency of short and long chain n-alkanolsGABA(A) receptors and alcohol.Spontaneous mobility of GABAA receptor M2 extracellular half relative to noncompetitive antagonist action.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Functional interactions of alcohol-sensitive sites in the N-methyl-D-aspartate receptor M3 and M4 domainsTryptophan-scanning mutagenesis in the alphaM3 transmembrane domain of the muscle-type acetylcholine receptor. A spring model revealed.Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study.Gaba receptor insecticide non-competitive antagonists may bind at allosteric modulator sites.Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors.Structural Basis of Alcohol Inhibition of the Pentameric Ligand-Gated Ion Channel ELIC.
P2860
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P2860
Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
Functional and structural anal ...... gating and alcohol modulation.
@en
Functional and structural anal ...... gating and alcohol modulation.
@nl
type
label
Functional and structural anal ...... gating and alcohol modulation.
@en
Functional and structural anal ...... gating and alcohol modulation.
@nl
prefLabel
Functional and structural anal ...... gating and alcohol modulation.
@en
Functional and structural anal ...... gating and alcohol modulation.
@nl
P2860
P356
P1476
Functional and structural anal ...... gating and alcohol modulation.
@en
P2093
R Adron Harris
Sangwook Jung
P2860
P304
P356
10.1074/JBC.M409871200
P407
P577
2004-11-02T00:00:00Z