Human sulfatase-1 inhibits the migration and proliferation of SMMC-7721 hepatocellular carcinoma cells by downregulating the growth factor signaling.
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Sulfatase 1 (hSulf-1) reverses basic fibroblast growth factor-stimulated signaling and inhibits growth of hepatocellular carcinoma in animal modelOverexpression of sulfatase-1 in murine hepatocarcinoma Hca-F cell line downregulates mesothelin and leads to reduction in lymphatic metastasis, both in vitro and in vivoHuman sulfatase 1 exerts anti-tumor activity by inhibiting the AKT/ CDK4 signaling pathway in melanoma.The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics.An oncolytic adenovirus regulated by a radiation-inducible promoter selectively mediates hSulf-1 gene expression and mutually reinforces antitumor activity of I131-metuximab in hepatocellular carcinoma.Sulfatase-1 knockdown promotes in vitro and in vivo aggressive behavior of murine hepatocarcinoma Hca-P cells through up-regulation of mesothelin.
P2860
Human sulfatase-1 inhibits the migration and proliferation of SMMC-7721 hepatocellular carcinoma cells by downregulating the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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P2093
P2860
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Human sulfatase-1 inhibits the ...... g the growth factor signaling.
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P2093
Changqing Su
Jiahe Yang
Longlong Bao
Mengchao Wu
Xiaohui Fu
P2860
P304
P356
10.1111/J.1872-034X.2012.01080.X
P577
2012-08-20T00:00:00Z