The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae.
about
Isc1 regulates sphingolipid metabolism in yeast mitochondria.The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation.Characterization of yeast mutants lacking alkaline ceramidases YPC1 and YDC1.The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.Cellular functions of cardiolipin in yeastMathematical modeling of pathogenicity of Cryptococcus neoformansDevelopmentally regulated sphingolipid degradation in Leishmania majorDegradation of host sphingomyelin is essential for Leishmania virulence.The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism.The yeast sphingolipid signaling landscape.Yeast sphingolipids: recent developments in understanding biosynthesis, regulation, and function.The retrograde response: a conserved compensatory reaction to damage from within and from without.Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.Mitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during agingThe retrograde response: when mitochondrial quality control is not enoughCoordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift.Specific degradation of phosphatidylglycerol is necessary for proper mitochondrial morphology and functionThematic review series: sphingolipids. ISC1 (inositol phosphosphingolipid-phospholipase C), the yeast homologue of neutral sphingomyelinases.ISC1-dependent metabolic adaptation reveals an indispensable role for mitochondria in induction of nuclear genes during the diauxic shift in Saccharomyces cerevisiaeSphingolipids and mitochondrial function, lessons learned from yeastRoles for sphingolipids in Saccharomyces cerevisiae.Sphingolipids and mitochondrial function in budding yeast.Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells.Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis.Distinct roles for de novo versus hydrolytic pathways of sphingolipid biosynthesis in Saccharomyces cerevisiae.Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria.
P2860
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P2860
The phosphatidylglycerol/cardiolipin biosynthetic pathway is required for the activation of inositol phosphosphingolipid phospholipase C, Isc1p, during growth of Saccharomyces cerevisiae.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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name
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@en
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@nl
type
label
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@en
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@nl
prefLabel
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@en
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@nl
P2093
P2860
P356
P1476
The phosphatidylglycerol/cardi ...... h of Saccharomyces cerevisiae.
@en
P2093
Silvia Vaena de Avalos
William Dowhan
Xuefeng Su
Yasuo Okamoto
P2860
P304
P356
10.1074/JBC.M411058200
P407
P577
2004-12-15T00:00:00Z