Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness.
about
Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitorThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Blocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.Specialized pro-resolving lipid mediators in the inflammatory response: An updateRole of Leukotrienes and Leukotriene Modifiers in Asthma.Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthmaIncreased expression of leukotriene C4 synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysmIron supplementation decreases severity of allergic inflammation in murine lungThe role of epoxide hydrolases in health and disease.Update in asthma 2010.Protective Effects of Intratracheally-Administered Bee Venom Phospholipase A2 on Ovalbumin-Induced Allergic Asthma in Mice.The development of novel LTA4H modulators to selectively target LTB4 generation.Newer treatments in the management of pediatric asthma.Leukotriene receptor antagonists pranlukast and montelukast for treating asthma.Bronchial epithelial cells: The key effector cells in the pathogenesis of chronic obstructive pulmonary disease?Considerations for the Conduct of Clinical Trials with Antiinflammatory Agents in Cystic Fibrosis. A Cystic Fibrosis Foundation Workshop Report.Development of predictive quantitative structure-activity relationship model and its application in the discovery of human leukotriene A4 hydrolase inhibitors.Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction.Omega-3 fatty acids in the maintenance of ulcerative colitis.Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.Putative association of SMAPIL polymorphisms with risk of aspirin intolerance in asthmatics.Targeting leukotriene B4 in inflammation.Human eosinophils and mast cells: Birds of a feather flock together.Macrophage LTB4 drives efficient phagocytosis of Borrelia burgdorferi via BLT1 or BLT2.
P2860
Q27681975-45794523-82A2-478C-9AE6-1DF16215DA0DQ30486745-7ADD5CDF-5194-49AF-AF20-7F8DAAE5DD15Q33593640-FAFE9C15-8F68-4D10-AEC6-303EBDF688C0Q33657562-206BFFEB-DE14-4CB7-A0ED-E48EAF1D366EQ33664150-CAAE95F2-67CB-4DF3-ACA7-5B07ABF65AA0Q34123695-D05A6DB4-2F9F-4CFB-8D7E-E82C676439C7Q34397052-94E3427B-466B-4C49-8295-71364DF353F0Q34429761-715E34B8-7074-4040-8182-42C4D4D05FB6Q34440084-863F9A1E-202D-48E3-9D48-F675CBACC9ECQ35219714-8E535B73-3D3D-4A19-953C-6EF91D54ADF6Q37378862-A9A4E9E3-4BC0-4C8C-87AF-54DB50829547Q37707902-4B969454-50EA-4843-B3AB-D9CC7FC4CDD6Q38113498-8A920507-429B-4030-ACAA-36DCBF03843BQ38172278-3B9006F0-BE2B-410C-9264-5877538E8587Q38418872-A4FADB5C-B2D7-4F81-8BEF-60A0A1A839BDQ38543069-82B40558-FF9F-4B8D-B1B0-C62E65C6AF69Q39500070-13F92775-F7BA-4D89-A3C6-76CF7BC97E38Q42316383-AAE52ABD-A4A0-4CFF-90A8-738FA76EC7D8Q42357496-47AF5314-A30E-4284-8680-3BE6ACD13F74Q42670355-ECCFB90D-A4A1-4D45-A89A-F6BBA06D5D08Q42910932-C1C2DC19-65DB-48E0-AC05-F38EF3A70F6EQ43464822-52AF6E21-31EB-458E-8A76-B3AF7DEF1596Q50068947-B3186746-D851-4C42-B5DC-24D8E8736FEBQ50318202-8B66FD4C-02E6-4397-AFDE-6EC52AA29D9D
P2860
Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Leukotriene A
@nl
Leukotriene A(4) hydrolase inh ...... ation and hyperresponsiveness.
@en
type
label
Leukotriene A
@nl
Leukotriene A(4) hydrolase inh ...... ation and hyperresponsiveness.
@en
prefLabel
Leukotriene A
@nl
Leukotriene A(4) hydrolase inh ...... ation and hyperresponsiveness.
@en
P2093
P2860
P1476
Leukotriene A(4) hydrolase inh ...... ation and hyperresponsiveness.
@en
P2093
Anne M Fourie
Binggang Sun
Homayon Banie
Jason P Riley
Katherine A Lundeen
Lars Karlsson
Navin L Rao
Paul J Dunford
Shelby Crawford
P2860
P304
P356
10.1164/RCCM.200807-1158OC
P407
P577
2010-01-28T00:00:00Z