A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.
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Insights into CYP2B6-mediated drug-drug interactionsPredictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals.Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data.Synergistically enhanced CYP2B6 inducibility between a polymorphic mutation in CYP2B6 promoter and pregnane X receptor activation.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeGenetic variability of CYP2B6 polymorphisms in four southern Chinese populations.Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism.Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New GuineaTranscriptional Regulation of CYP2B6 Expression by Hepatocyte Nuclear Factor 3β in Human Liver Cells.Influence of CYP2B6 and ABCB1 SNPs on nevirapine plasma concentrations in Burundese HIV-positive patients using dried sample spot devices.Overview of the pharmacogenetics of HIV therapy.Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevanceCandidate SNP Markers of Gender-Biased Autoimmune Complications of Monogenic Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene PromotersGenetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus.Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance.Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1Prevalence of poor and rapid metabolizers of drugs metabolized by CYP2B6 in North Indian population residing in Indian national capital territory.Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.Frequencies of Cytochrome P450 2B6 and 2C8 Allelic Variants in the Mozambican Population.PhRMA white paper on ADME pharmacogenomics.Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters.Pharmacogenetics of antiretroviral therapy.Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.Physiological Content and Intrinsic Activities of 10 Cytochrome P450 Isoforms in Human Normal Liver Microsomes.Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance.A penalized mixture model approach in genotype/phenotype association analysis for quantitative phenotypesHow to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in Affinity of the TATA-Binding Protein for This Promoter.Structure-Activity Studies Reveal the Oxazinone Ring Is a Determinant of Cytochrome P450 2B6 Activity Toward Efavirenz.Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism.Novel CYP2B6 enzyme variants in a Rwandese population: functional characterization and assessment of in silico prediction tools.Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6 *6 and *26.Genetic variability of CYP2D6, CYP2B6, CYP2C9 and CYP2C19 genes across the Italian Peninsula.Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro.Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters.
P2860
Q28078857-E75E9312-0412-421A-A3B2-B250669B5220Q33269667-9194F642-F885-4C81-869A-A8634C29152BQ33803436-FFCE041C-6D6F-413E-B1CA-5B4EF924F618Q34310059-40D54533-B477-4FE6-BA12-8161E3FE0D53Q34824471-8E1CA34C-E5F3-4A2F-B307-35A6E3CA91DAQ35055965-2EBB5098-200D-4305-A16F-E925116AABC8Q35584977-00397186-FB84-4866-B2F0-FA73A45F48C9Q35669950-3AD4A9CC-7537-4B88-9A0F-FD4FC402EFFEQ35941376-685B08F2-BBA7-4C17-9868-D149FE235943Q36087985-397BD071-9A99-40BF-AC68-B5E0A8D0893FQ36389312-B4CA9746-8A02-4B46-8BCF-BBDFE458ABE2Q36657589-2C880185-6430-4FF6-8D35-6EA4B3302D4BQ36760451-91C4D73D-BE62-4E5D-81C0-D7FD3319CC39Q36802054-F55CB921-4564-4675-951B-5084AAB14CC8Q36885659-F094AA16-C5A3-46A9-82F3-9D57B9516B37Q36998199-72BE3A35-69E1-4DEF-A6B4-C60C6E1832A1Q37052162-CED5A835-6AC5-4BF2-BF42-F496354ABE6AQ37160674-3A19BFA0-706D-48C3-8719-EEBDF2620387Q37171678-FB35D8E7-204D-4993-B7EF-B2C3C17BC1C1Q37182212-0955C76A-8234-48F6-881D-5764C7F6828DQ37231785-362E31FE-1D1F-4028-A1EB-00DBD907219EQ38221179-823309C9-6250-480F-AECC-40F85679A9DFQ39037022-33F067F3-80C9-4E2B-99F2-6BF5320DFCE3Q39758335-88B1A761-36CE-4078-AC78-4436F05260B3Q40277327-54E90E36-461B-465A-A412-718BE07FA3B8Q40475945-3996CAD8-39BF-43C0-A833-11723F61BE8EQ42179348-984DFAAE-357C-4591-8744-CE3AC4E4052EQ42260918-3AC74550-11E7-4DCD-923D-1A558E554C1CQ43122200-BEDAEF8D-4D90-45BB-A5A7-3CF054D500DDQ45088644-9B79DFDF-16D9-4FF4-B71D-1F26344C2C6CQ46965067-2C1B7542-B39E-4FE0-8909-CF2BCB737A57Q47190575-DDE7F35C-C7A7-4EFA-86F6-B5A22006832AQ53547764-7FA690EA-7840-4791-9425-37CFA9D98C58Q54936700-2E0BCBF3-A858-48F9-9017-8E0D8C368A48
P2860
A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
A natural CYP2B6 TATA box poly ...... he transcriptional start site.
@en
A natural CYP2B6 TATA box polymorphism
@nl
type
label
A natural CYP2B6 TATA box poly ...... he transcriptional start site.
@en
A natural CYP2B6 TATA box polymorphism
@nl
prefLabel
A natural CYP2B6 TATA box poly ...... he transcriptional start site.
@en
A natural CYP2B6 TATA box polymorphism
@nl
P2093
P356
P1476
A natural CYP2B6 TATA box poly ...... the transcriptional start site
@en
P2093
Andreas K Nussler
Jörg Zukunft
Kathrin Klein
Matthias Schwab
Michel Eichelbaum
Tanja Richter
Thomas Lang
P304
P356
10.1124/MOL.104.008086
P577
2005-02-18T00:00:00Z