Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease. - Wikidata - wikimedia - TriplyDB

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease.

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease.

http://www.wikidata.org/entity/Q45305307

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The choreography of neuroinflammation in Huntington's disease Iron dysregulation in Huntington's disease Microglial pathology New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.Transferrin Receptor 2 Dependent Alterations of Brain Iron Metabolism Affect Anxiety Circuits in the Mouse.Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/2 mouse model of HD Neuroimmunology of Huntington's Disease: Revisiting Evidence from Human Studies Potential function for the Huntingtin protein as a scaffold for selective autophagy.Redox proteomics in selected neurodegenerative disorders: from its infancy to future applications.Mutant huntingtin impairs immune cell migration in Huntington disease.Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Iron-Restricted Diet Affects Brain Ferritin Levels, Dopamine Metabolism and Cellular Prion Protein in a Region-Specific Manner.MRI T2 Hypointensities in basal ganglia of premanifest Huntington's disease Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice Iron and mechanisms of neurotoxicity Iron and neurodegeneration in the multiple sclerosis brain.Iron accumulates in Huntington's disease neurons: protection by deferoxamine Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons The role of the immune system in triplet repeat expansion diseases Microglia in the normally aged hippocampus.Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla.Alzheimer's disease, neuroprotection, and CNS immunosenescence.Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo Korean Red Ginseng Extract Attenuates 3-Nitropropionic Acid-Induced Huntington's-Like Symptoms Bone marrow transplantation confers modest benefits in mouse models of Huntington's disease.Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation Mammalian iron metabolism and its control by iron regulatory proteins A delicate balance: Iron metabolism and diseases of the brain.Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington's disease.PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo Cannabinoid receptor 2 signaling in peripheral immune cells modulates disease onset and severity in mouse models of Huntington's disease.Iron is essential for oligodendrocyte genesis following intraspinal macrophage activation.Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.

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P2860

Ferritin accumulation in dystrophic microglia is an early event in the development of Huntington's disease.

http://www.wikidata.org/entity/Q45305307

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Ferritin accumulation in dystr ...... pment of Huntington's disease.

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Ferritin accumulation in dystr ...... pment of Huntington's disease.

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type

label

Ferritin accumulation in dystr ...... pment of Huntington's disease.

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Ferritin accumulation in dystr ...... pment of Huntington's disease.

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prefLabel

Ferritin accumulation in dystr ...... pment of Huntington's disease.

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Ferritin accumulation in dystr ...... pment of Huntington's disease.

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Ferritin accumulation in dystr ...... pment of Huntington's disease.

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Betzi Alcon

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Danielle A Simmons

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Gary Lynch

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Malcolm Casale

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Natasha Narayan

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Nha Pham

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P2860

Early and progressive accumulation of reactive microglia in the Huntington disease brain.

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1074-1084

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scholarly article

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10.1002/GLIA.20526

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10

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55

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2007-08-01T00:00:00Z

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17551926

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Huntington disease