Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. - Wikidata - wikimedia - TriplyDB

Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2.

Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2.

http://www.wikidata.org/entity/Q45345777

about

RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13 RIM1alpha and RIM1beta are synthesized from distinct promoters of the RIM1 gene to mediate differential but overlapping synaptic functions Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release Distinct initial SNARE configurations underlying the diversity of exocytosis Liprin α3: a putative estrogen regulated acrosomal protein CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon Fear potentiated startle increases phospholipase D (PLD) expression/activity and PLD-linked metabotropic glutamate receptor mediated post-tetanic potentiation in rat amygdala.Cryo-electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals Differential requirement for protein synthesis in presynaptic unmuting and muting in hippocampal glutamate terminals Diacylglycerol signaling underlies astrocytic ATP release ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains.Sumoylated MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons.Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics.Differential Expression of Munc13-2 Produces Unique Synaptic Phenotypes in the Basolateral Amygdala of C57BL/6J and DBA/2J Mice.UNC-13 and UNC-10/rim localize synaptic vesicles to specific membrane domains.RIM proteins and their role in synapse function.Molecular mechanisms for synchronous, asynchronous, and spontaneous neurotransmitter release.PI(4,5)P₂-binding effector proteins for vesicle exocytosis.ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.The readily releasable pool of synaptic vesicles.Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking Ethanol Mediated Inhibition of Synaptic Vesicle Recycling at Amygdala Glutamate Synapses Is Dependent upon Munc13-2.RIM, Munc13, and Rab3A interplay in acrosomal exocytosis The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila.Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density.Glutamate Neurotransmitter Release Cycle Presynaptic mechanisms of endocannabinoid-mediated long-term depression in the hippocampus.Regulation of acrosome reaction by Liprin α3, LAR and its ligands in mouse spermatozoa.Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.Synaptic weight set by Munc13-1 supramolecular assemblies.Critical Role of Trp-588 of Presynaptic Munc13-1 for Ligand Binding and Membrane Translocation.Transcellular Nanoalignment of Synaptic Function.Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1.RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.ELKS active zone proteins as multitasking scaffolds for secretion.Doc2-mediated superpriming supports synaptic augmentation

P2860

Q26269920-55DE0BBA-9EB4-4C0A-AE21-ABC801AE39AC Q26269937-F7B63237-A8DD-431D-8237-E32AE56C0CFD Q26269947-D6659EC9-912C-41DE-A79E-C4DCE0A719A9 Q26866150-2F327F00-4DF2-4639-9CEA-06CE726BFB85 Q28117949-E43E76DA-3E90-46F4-A015-5A3A6F0359B4 Q28567130-F0140011-D7E5-4162-8853-1698F9539A2B Q28909809-9D07A897-9246-4856-8B4B-771EC973A2E0 Q30364663-BA6511C3-472D-4781-A51E-1B487DB07B74 Q30540085-B0CCD329-6021-46FD-AFB6-5D5549502754 Q33702262-BD761B95-EA21-4330-B4B1-BF1B17B05412 Q33885331-2EBFAA61-9F29-43BB-BD49-725B752D819B Q34525842-B5592B12-3337-4652-9DD2-046E3348C053 Q35151531-355FF22B-A0CC-4D11-986F-7B10A4620491 Q37071725-F5EEDC53-C364-4A05-BCC1-A3A6B0D150F2 Q37086805-79C642D1-B176-49B4-BB88-C1A6FE1B6798 Q37290090-F71ED992-7D26-4275-BCC8-DA49BE9ED0B5 Q37398460-E51634CD-D132-4D3F-9370-2F43A534F73C Q37417587-E3F5D972-2085-452E-A86D-2560733CCC98 Q37724774-EB0F859E-8640-4F52-AD34-5F6FD4D4F1ED Q38166028-BA59F73D-4B6A-4633-8FD0-7FDE453C919C Q38256514-D4D0C575-6858-418E-B3B7-B60B631709CA Q38713426-B7B208E9-2D36-4A86-BF1D-C7519A8065D6 Q39095247-FC018621-397F-4E88-AC42-6258E1A4554D Q39756941-A263CE43-458E-4F2B-B149-75A12CBD9898 Q40091505-31E4822C-0C41-49AE-92E1-CC6658F2F026 Q42272576-032B8D97-1AE0-4C3D-8FAD-CC0675D81BF2 Q42590696-423846BD-F744-4232-A12E-0E9564A78FAE Q43241214-3B505204-4B7C-47EB-A263-B4F231442965 Q45317772-AE5F677F-9162-4C6B-9E8D-CAFE80E40646 Q45954160-1AF8625E-B9E0-4724-BEA0-BD2761960A9C Q45970320-14BBE1E8-3A28-465A-A491-8BC6B0305522 Q46765636-F89F7C74-EBB6-4B51-B703-42C8607978CF Q47174177-76B0464A-E429-407B-B248-C65D933A5602 Q47290370-CA3E5399-DBCA-43CF-8633-AAB9BDEF22CE Q47990307-2D9998B1-ACC8-47CE-AE04-5D5D3285882E Q50888051-3993AC78-CAAC-465F-89E2-70DCD130D395 Q52614917-8413FE93-EE10-45A6-971C-DF72C6E66D2D Q52656382-43C13095-9B72-429A-B430-0601B72C9A31 Q53840590-0576DE70-0E34-4D46-BD24-09DF7842E604 Q57446664-4AAAA381-D1F5-4613-914A-87672892D329

P2860

Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2.

http://www.wikidata.org/entity/Q45345777

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

2006年學術文章

@zh-hant

name

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@en

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@nl

type

label

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@en

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@nl

prefLabel

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@en

Binding to Rab3A-interacting m ...... nt of Munc13-1 and ubMunc13-2.

@nl

P1433

Q45345777-7EE5A0CF-274A-452D-8BA2-7579131EAE0C

P1476

Q45345777-12EA4E89-7CA9-4D67-A2EC-3AB7ACADFF59

P2093

Q45345777-30AAD8FF-162B-4D08-A2E2-1CD86286BCC1

Q45345777-5D998192-DC86-4DC6-84C1-6B21BD50FFBF

Q45345777-95AE3A2F-06BE-43A9-95ED-96F880FD1BA3

Q45345777-C31134D4-280C-4EFB-816B-69F74EB591C2

P2860

Q45345777-00253E6E-ACED-46AF-B392-ECAE3AE0E777

Q45345777-10660691-7660-493F-A71B-6C848BE18208

Q45345777-14FF7B91-C047-45BD-B170-F99E3C9D1C9D

Q45345777-17B2B3F8-78F2-4D3E-B37F-6A01B075C145

Q45345777-1811BB9B-C788-40E7-8821-F1B2344F43C8

Q45345777-24AAFC7D-652B-44AE-B5D1-BD1405D5C478

Q45345777-24ED0D3D-ECB0-4667-BC4F-AB8947514B43

Q45345777-27328F18-CFE9-40C0-9CA7-6CEDFA973552

Q45345777-2C3452E4-8F49-4C28-B8B8-6ADB83EDBAF9

Q45345777-33BE0000-00FC-4112-AF3D-7B1B1D122820

P304

Q45345777-F9C6D8D2-37B5-4BFE-915C-C08C7564583C

P31

Q45345777-D44050EB-DAD6-4719-96AA-555D7EA8576D

P356

Q45345777-87AAFA18-C2D8-497A-8782-A84356E411DF

P407

Q45345777-A2134C80-653D-42D6-A4AD-DE5058832130

P433

Q45345777-6C61C75D-54DD-4476-A748-6879EAE72B0E

P478

Q45345777-F5344A9F-C4F3-4CD7-A59C-BA6D992A7F38

P50

Q45345777-622EA797-D207-4500-BA03-B5F8AD72070A

P577

Q45345777-0C25A4EF-0B84-403C-AEE4-2EC998B7D7CC

P5875

Q45345777-C945F55E-B6A8-4AE3-B764-92A8AC77D406

P698

Q45345777-3125AA7C-4297-430A-8139-4363571EE18F

P356

P1433

Journal of Biological Chemistry

P1476

Binding to Rab3A-interacting m ...... ent of Munc13-1 and ubMunc13-2

@en

P2093

Hiroshi Kawabe

http://www.w3.org/2001/XMLSchema#string

Kerstin Reim

http://www.w3.org/2001/XMLSchema#string

Nils Brose

http://www.w3.org/2001/XMLSchema#string

Yaisa S Andrews-Zwilling

http://www.w3.org/2001/XMLSchema#string

P2860

Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin

The synaptic vesicle cycle

A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones.

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Cast: a novel protein of the cytomatrix at the active zone of synapses that forms a ternary complex with RIM1 and munc13-1

Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release

Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

P304

19720-19731

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M601421200

http://www.w3.org/2001/XMLSchema#string

P407

P433

28

http://www.w3.org/2001/XMLSchema#string

P478

281

http://www.w3.org/2001/XMLSchema#string

P50

Frederique Varoqueaux

P577

2006-05-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7076623

http://www.w3.org/2001/XMLSchema#string

P698

16704978

http://www.w3.org/2001/XMLSchema#string