HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D.
about
Towards a rational design of an asymptomatic clinical herpes vaccine: the old, the new, and the unknownThe challenges and opportunities for the development of a T-cell epitope-based herpes simplex vaccineDiversity in CD8(+) T cell function and epitope breadth among persons with genital herpes.Asymptomatic human CD4+ cytotoxic T-cell epitopes identified from herpes simplex virus glycoprotein BThe herpevac trial for women: Sequence analysis of glycoproteins from viruses obtained from infected subjects.Liposomal gD ectodomain (gD1-306) vaccine protects against HSV2 genital or rectal infection of female and male mice.Nasolacrimal duct closure modulates ocular mucosal and systemic CD4(+) T-cell responses induced following topical ocular or intranasal immunization.Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine.Effects of herpes simplex virus type 2 glycoprotein vaccines and CLDC adjuvant on genital herpes infection in the guinea pig.Engagement of TLR2 reverses the suppressor function of conjunctiva CD4+CD25+ regulatory T cells and promotes herpes simplex virus epitope-specific CD4+CD25- effector T cell responses.HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeniOf mice and not humans: how reliable are animal models for evaluation of herpes CD8(+)-T cell-epitopes-based immunotherapeutic vaccine candidates?The herpes simplex virus 1 latency-associated transcript promotes functional exhaustion of virus-specific CD8+ T cells in latently infected trigeminal ganglia: a novel immune evasion mechanismIn silico analysis of six known Leishmania major antigens and in vitro evaluation of specific epitopes eliciting HLA-A2 restricted CD8 T cell response.Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpesCross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine.Therapeutic immunization with a mixture of herpes simplex virus 1 glycoprotein D-derived “asymptomatic” human CD8+ T-cell epitopes decreases spontaneous ocular shedding in latently infected HLA transgenic rabbits: association with low frequency of lA Herpes Simplex Virus Type 1 Human Asymptomatic CD8+ T-Cell Epitopes-Based Vaccine Protects Against Ocular Herpes in a "Humanized" HLA Transgenic Rabbit Model.Defining the herpes simplex virus-specific CD8+ T cell repertoire in C57BL/6 miceImmunodominant "asymptomatic" herpes simplex virus 1 and 2 protein antigens identified by probing whole-ORFome microarrays with serum antibodies from seropositive asymptomatic versus symptomatic individualsDiscovery of potential diagnostic and vaccine antigens in herpes simplex virus 1 and 2 by proteome-wide antibody profiling.A genital tract peptide epitope vaccine targeting TLR-2 efficiently induces local and systemic CD8+ T cells and protects against herpes simplex virus type 2 challengeDeveloping an asymptomatic mucosal herpes vaccine: the present and the future.The herpes simplex virus type 1 latency-associated transcript inhibits phenotypic and functional maturation of dendritic cells.Future of an "Asymptomatic" T-cell Epitope-Based Therapeutic Herpes Simplex VaccineTargeting the genital tract mucosa with a lipopeptide/recombinant adenovirus prime/boost vaccine induces potent and long-lasting CD8+ T cell immunity against herpes: importance of MyD88.Mucosal herpes immunity and immunopathology to ocular and genital herpes simplex virus infections.HLA-A*0201-restricted CD8+ T-cell epitopes identified in dengue viruses.Current trends in negative immuno-synergy between two sexually transmitted infectious viruses: HIV-1 and HSV-1/2.Identification and translational validation of novel mammaglobin-A CD8 T cell epitopesThe Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8+ T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic RabbitsGender-dependent HLA-DR-restricted epitopes identified from herpes simplex virus type 1 glycoprotein D.Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeuticsA novel HLA (HLA-A*0201) transgenic rabbit model for preclinical evaluation of human CD8+ T cell epitope-based vaccines against ocular herpes.Vaxfectin-adjuvanted plasmid DNA vaccine improves protection and immunogenicity in a murine model of genital herpes infectionPotent adjuvant activity of cationic liposome-DNA complexes for genital herpes vaccinesHuman Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against OculDendritic cell-based vaccines in treating recurrent herpes labialis: Results of pilot clinical study.HSV-2 vaccine: current status and insight into factors for developing an efficient vaccine.
P2860
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P2860
HLA-A*0201-restricted CD8+ cytotoxic T lymphocyte epitopes identified from herpes simplex virus glycoprotein D.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@en
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@nl
type
label
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@en
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@nl
prefLabel
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@en
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@nl
P2093
P1476
HLA-A*0201-restricted CD8+ cyt ...... simplex virus glycoprotein D.
@en
P2093
Alex Nguyen
Amir Mohebbi
Anthony B Nesburn
Aziz Alami Chentoufi
Gargi Dasgupta
Ilham Bettahi
Kasper Lamberth
Lbachir BenMohamed
Michelle Wu
Steven L Wechsler
P304
P356
10.4049/JIMMUNOL.180.1.426
P407
P577
2008-01-01T00:00:00Z