Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
about
The evolving roles and controversies of radiotherapy in the treatment of glioblastomaClinical Neuropathology practice guide 5-2015: MGMT methylation pyrosequencing in glioblastoma: unresolved issues and open questionsDNA methylation biomarkers: cancer and beyondThe MGMT promoter SNP rs16906252 is a risk factor for MGMT methylation in glioblastoma and is predictive of response to temozolomideThe prognostic value of MGMT promoter status by pyrosequencing assay for glioblastoma patients' survival: a meta-analysisSurvival in glioblastoma: a review on the impact of treatment modalities.Treatment of glioblastoma in elderly patients.The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort.MGMT promoter methylation correlates with an overall survival benefit in Chinese high-grade glioblastoma patients treated with radiotherapy and alkylating agent-based chemotherapy: a single-institution study.Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region.Predictive value of tumor recurrence using urinary vascular endothelial factor levels in patients receiving radiation therapy for Glioblastoma Multiforme (GBM)ZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma.Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review).MGMT promoter methylation determined by HRM in comparison to MSP and pyrosequencing for predicting high-grade glioma responseManagement of elderly patients with gliomasRole of MGMT as biomarker in colorectal cancer.Radiotherapy plus concurrent or sequential temozolomide for glioblastoma in the elderly: a meta-analysis.Do glioma patients derive any therapeutic benefit from taking a higher cumulative dose of temozolomide regimens?: a meta-analysis.Predictive value of MGMT promoter methylation status in Asian and Caucasian patients with malignant gliomas: a meta-analysisSomatic mutations in glioblastoma are associated with methylguanine-DNA methyltransferase methylation.MGMT promoter methylation in serum and cerebrospinal fluid as a tumor-specific biomarker of gliomaProgrammed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma.MGMT testing allows for personalised therapy in the temozolomide era.Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosisPro-apoptotic effects of rHSG on C6 glioma cells.MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-statusO6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomasExpression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas.The prognostic value of MGMT promoter methylation in glioblastoma: A meta-analysis of clinical trials.Personalized care in neuro-oncology coming of age: why we need MGMT and 1p/19q testing for malignant glioma patients in clinical practice.Role of Biomarkers in the Clinical Management of Glioblastomas: What are the Barriers and How Can We Overcome Them?Patterns of care and outcome for patients with glioblastoma diagnosed during 2008-2010 in SpainPersonalized treatment strategies in glioblastoma: MGMT promoter methylation status.High-grade glioma in elderly patients: can the oncogeriatrician help?Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial.Patterns of diagnostic marker assessment in adult diffuse glioma: a survey of the European Confederation of Neuropathological Societies (Euro-CNS).EFEMP1 induces γ-secretase/Notch-mediated temozolomide resistance in glioblastoma.Molecular markers of glioma: an update on recent progress and perspectives.Imaging genomic mapping in glioblastoma.
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Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@en
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@nl
type
label
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@en
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@nl
prefLabel
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@en
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@nl
P2093
P50
P356
P1476
Predictive impact of MGMT promoter methylation in glioblastoma of the elderly.
@en
P2093
Bettina Hentschel
Gabriele Schackert
German Glioma Network
Manfred Westphal
Markus Loeffler
Matthias Simon
Oliver Schnell
Torsten Pietsch
P304
P356
10.1002/IJC.27385
P577
2012-01-11T00:00:00Z