Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain.
about
Biology of adeno-associated viral vectors in the central nervous systemNeuroanatomy goes viral!The prospect of molecular therapy for Angelman syndrome and other monogenic neurologic disordersSystemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan.Effects of neonatal neural progenitor cell implantation on adult neuroanatomy and cognition in the Ts65Dn model of Down syndromeChanging channels in pain and epilepsy: Exploiting ion channel gene therapy for disorders of neuronal hyperexcitabilityAblation of fast-spiking interneurons in the dorsal striatum, recapitulating abnormalities seen post-mortem in Tourette syndrome, produces anxiety and elevated groomingTargeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndromeTargeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasoundRapid, long-term labeling of cells in the developing and adult rodent visual cortex using double-stranded adeno-associated viral vectors.Efficacy of a combined intracerebral and systemic gene delivery approach for the treatment of a severe lysosomal storage disorder.Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene.Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.Directed evolution of adeno-associated virus for glioma cell transductionComparative study of the transfection efficiency of commonly used viral vectors in rhesus monkey (Macaca mulatta) brainsSystemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.Preventing growth of brain tumors by creating a zone of resistance.Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNSAAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injuryGene transfer to the CNS using recombinant adeno-associated virusAdeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapy.Specific disruption of astrocytic Ca2+ signaling pathway in vivo by adeno-associated viral transduction.Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injectionAAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification methodCatalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease: prophylactic and therapeutic applications.A spirulina-enhanced diet provides neuroprotection in an α-synuclein model of Parkinson's disease.Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain.Pre-immunization with an intramuscular injection of AAV9-human erythropoietin vectors reduces the vector-mediated transduction following re-administration in rat brainInsulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic miceDisrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depressionAnalysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain.The AAV9 receptor and its modification to improve in vivo lung gene transfer in miceRobust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.Adeno-associated viral serotypes produce differing titers and differentially transduce neurons within the rat basal and lateral amygdalaGene therapy for the nervous system: challenges and new strategies.
P2860
Q21129328-BDAF1382-B27C-4AA3-ADB7-A5515C3AEB59Q26802140-ABE7C482-DB67-4BBB-8CA9-B8DEC8834098Q27021312-0D38AED3-C984-49B8-B574-74B99059C3DFQ27300989-3C15354B-6730-4B59-BD38-24488B8CBD26Q27303804-C51B9271-E87C-4267-9367-F38C12133C95Q28081164-DED93D67-B2D5-4F9F-BEB3-4CCC0E2A5DF3Q30354927-255F9ED8-362D-4EFA-AD5F-55B4FC13235CQ30406592-3926D3DD-7AEC-4617-BC18-4E30E3D8B937Q30447740-01A56FCA-F51E-4DF7-8370-37ED83EE53D0Q30495536-CB5D9C51-47AC-44EF-8171-CAAB623440AEQ30500346-4D0B835B-55DC-42E0-8310-7BA75D86D50FQ30573520-06D0973E-1B31-4AD5-889D-FC8074B64570Q30574131-007D12FF-71CD-4D1F-B629-C42A222544F8Q30605561-45FC465E-9308-4662-A356-39AFFCEFA401Q33484220-9AA0BFF8-81EA-4A97-80C8-0B1A825F84E7Q33577391-EC5E2A4D-8A2A-46C3-8878-511F36FC7E3BQ33600773-A77D0079-4F72-4BAB-B6F9-685A8B14D27CQ33713108-9FE498C9-6609-4C3E-B65D-BB3DFB1183B7Q33825333-5A5EA8DA-5B52-41EE-A97F-B5AD72AD10E2Q33870720-EDB44192-E382-48AC-9A2F-3B5BF7A13784Q33894621-D044A50A-B0D3-48E4-9F23-FF30288D29FCQ33936020-00AF2ED9-954E-4CAE-8EC1-06679E4FFA36Q34055904-5C4BB461-B4A9-45CC-9F34-860FEA749499Q34063628-647B4890-BF84-4FFD-990D-541DB9E84654Q34166253-F475CB74-2FCD-45A3-AF75-DD1BB5BA5657Q34172458-698EC4CE-9138-4F1D-BC15-34C5F3EBEDBFQ34233343-36E48E8D-A044-46B3-9585-90543A1EEBDFQ34330377-313EDC48-7FE4-4215-826F-F3E2D035B2C4Q34345602-E2A8E4D6-3690-4F5A-B0F7-4ADB91C78477Q34428512-C05B05FE-3EDC-4B8E-A5FD-2AEB3CA7A5DAQ34664932-5D3F0D92-F753-4BEC-80A7-B87EF7A85E0EQ34718452-9B777B29-633D-4563-960B-F29854FDDB72Q34880331-67A3E8D6-CF42-4D01-A1CC-A3CD6257B849Q34973847-FC5FD21B-3714-4FB9-BF30-F570FC540FCAQ35004325-AF242E6F-45FD-4AB6-B3F6-E03E6185929BQ35006292-0B4F1C95-952E-4FA4-8294-EFC01C9DB0E5Q35015807-9A038A76-3EB4-41CA-AF09-50C006DB9FC9Q35025591-16CB5C68-9DD1-42B2-B8C3-ED50D6E863B2Q35095825-7F2A7CAE-9743-448D-994B-2BF49F0532E3Q35340196-1705BC3A-A692-4BB1-B8FE-EB5E8CA3B4CB
P2860
Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@en
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@nl
type
label
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@en
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@nl
prefLabel
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@en
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@nl
P1433
P1476
Transduction characteristics o ...... , and Rh10 in the mouse brain.
@en
P2093
Cassia N Cearley
John H Wolfe
P304
P356
10.1016/J.YMTHE.2005.11.015
P577
2006-01-18T00:00:00Z