The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.

The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.

Item
http://www.wikidata.org/entity/Q45475260
Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug DesignStructure-Based Evaluation of C5 Derivatives in the Catechol Diether Series Targeting HIV-1 Reverse TranscriptaseStructural Maturation of HIV-1 Reverse Transcriptase-A Metamorphic Solution to Genomic InstabilityHigh sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations.HIV-1 protease dimer interface mutations that compensate for viral reverse transcriptase instability in infectious virions.Basis for early and preferential selection of the E138K mutation in HIV-1 reverse transcriptase.Structure-enhanced methods in the development of non-nucleoside inhibitors targeting HIV reverse transcriptase variants.Structural and Preclinical Studies of Computationally Designed Non-Nucleoside Reverse Transcriptase Inhibitors for Treating HIV infection.Homodimerization of the p51 subunit of HIV-1 reverse transcriptase.Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors.
P2860

The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs.

Item
http://www.wikidata.org/entity/Q45475260
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
The N137 and P140 amino acids ...... w classes of anti-HIV-1 drugs.
@en
The N137 and P140 amino acids ...... immunodeficiency virus type 1
@nl
type
label
The N137 and P140 amino acids ...... w classes of anti-HIV-1 drugs.
@en
The N137 and P140 amino acids ...... immunodeficiency virus type 1
@nl
prefLabel
The N137 and P140 amino acids ...... w classes of anti-HIV-1 drugs.
@en
The N137 and P140 amino acids ...... immunodeficiency virus type 1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
The N137 and P140 amino acids ...... w classes of anti-HIV-1 drugs.
@en
P2093
P2860
P304
P31
P356
10.1016/J.FEBSLET.2005.02.077
P407
P433
P478
P50
P577
P5875
P698