Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons.
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Neuroanatomy goes viral!Chk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growthA herpes simplex virus vector system for expression of complex cellular cDNA librariesHerpes simplex virus type 1 vector-mediated expression of nerve growth factor protects dorsal root ganglion neurons from peroxide toxicityEngineered HSV vector achieves safe long-term transgene expression in the central nervous system.Pseudotyping of glycoprotein D-deficient herpes simplex virus type 1 with vesicular stomatitis virus glycoprotein G enables mutant virus attachment and entry.Gene therapy in the CNS.Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNSGene delivery with viral vectors for cerebrovascular diseases.Gene therapy in epilepsy.HSV-1-based vectors for gene therapy of neurological diseases and brain tumors: part II. Vector systems and applicationsHSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathyFrom gene transfer to gene therapy in lysosomal storage diseases affecting the central nervous system.ICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.Antihyperalgesic effects of infection with a preproenkephalin-encoding herpes virus.Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy.Herpes simplex viral-vector design for efficient transduction of nonneuronal cells without cytotoxicity.Viral and non-viral vectors in gene therapy: technology development and clinical trials.An HSV-based library screen identifies PP1α as a negative TRPV1 regulator with analgesic activity in models of painHistone deacetylase 6 inhibition enhances oncolytic viral replication in glioma.Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.Herpes simplex virus 1 (HSV-1) for cancer treatment.Gene therapy for the treatment of sensory neuropathy.Effects of herpes simplex virus vector-mediated enkephalin gene therapy on bladder overactivity and nociceptionOncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity.Gene therapy applications for the treatment of neuropathic pain.Extreme susceptibility of African naked mole rats (Heterocephalus glaber) to experimental infection with herpes simplex virus type 1.Immune responses to herpesviral vectors.HSV vector-mediated modification of primary nociceptor afferents: an approach to inhibit chronic pain.Spread and replication of and immune response to gamma134.5-negative herpes simplex virus type 1 vectors in BALB/c mice.Viral vectors for gene delivery to the central nervous system.Targeted drug delivery to the peripheral nervous system using gene therapy.Gene therapy for the treatment of chronic peripheral nervous system pain.Equine herpesvirus 1 gene 12 can substitute for vmw65 in the growth of herpes simplex virus (HSV) type 1, allowing the generation of optimized cell lines for the propagation of HSV vectors with multiple immediate-early gene defects.Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor.Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system.Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection.Immobilized cobalt affinity chromatography provides a novel, efficient method for herpes simplex virus type 1 gene vector purification.Lipid-mediated delivery of RNA is more efficient than delivery of DNA in non-dividing cells.Herpes Virus Amplicon Vectors.
P2860
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P2860
Deletion of multiple immediate-early genes from herpes simplex virus reduces cytotoxicity and permits long-term gene expression in neurons.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Deletion of multiple immediate ...... rm gene expression in neurons.
@en
Deletion of multiple immediate ...... rm gene expression in neurons.
@nl
type
label
Deletion of multiple immediate ...... rm gene expression in neurons.
@en
Deletion of multiple immediate ...... rm gene expression in neurons.
@nl
prefLabel
Deletion of multiple immediate ...... rm gene expression in neurons.
@en
Deletion of multiple immediate ...... rm gene expression in neurons.
@nl
P2093
P356
P1433
P1476
Deletion of multiple immediate ...... rm gene expression in neurons.
@en
P2093
Glorioso JC
Marconi PC
Ramakrishnan R
P2888
P304
P356
10.1038/SJ.GT.3300766
P577
1998-12-01T00:00:00Z
P5875
P6179
1029486280