Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis.
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Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritisGene therapy in animal models of rheumatoid arthritis: are we ready for the patients?Molecular profile of synovial fibroblasts in rheumatoid arthritis depends on the stage of proliferation.Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats.Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritisThe senescence-associated secretory phenotype: the dark side of tumor suppressionIdentification of novel biomarkers in chronic immune thrombocytopenia (ITP) by microarray-based serum protein profiling.Rheumatoid Arthritis, Immunosenescence and the Hallmarks of AgingMultiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review.p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis.A question of transformation: the synovial fibroblast in rheumatoid arthritisGene therapy for arthritis.15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in ratsPerspectives on the use of gene therapy for chronic joint diseases.Gene transfer as a future therapy for rheumatoid arthritis.Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritisA cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritisInteractions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases.Cyclin-dependent kinase inhibitor p21, via its C-terminal domain, is essential for resolution of murine inflammatory arthritisGene therapy for autoimmune diseases: quo vadis?Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.Targets of immune regeneration in rheumatoid arthritis.miR-146b-5p mediates p16-dependent repression of IL-6 and suppresses paracrine procarcinogenic effects of breast stromal fibroblastsActin cytoskeleton dynamics linked to synovial fibroblast activation as a novel pathogenic principle in TNF-driven arthritis.Molecular aspects of rheumatoid arthritis: role of transcription factors.Hypervariable genes--experimental error or hidden dynamics.Disorders in angiogenesis and redox pathways are main factors contributing to the progression of rheumatoid arthritis: a comparative proteomics study.Angiostatin gene transfer as an effective treatment strategy in murine collagen-induced arthritis.Inflammation and bone destruction in arthritis: synergistic activity of immune and mesenchymal cells in joints.Overexpression of SPACIA1/SAAL1, a newly identified gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans.Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells.Cell cycle regulation therapy combined with cytokine blockade enhances antiarthritic effects without increasing immune suppression.Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints.Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis.Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway.Recombinant human endostatin inhibits adjuvant arthritis by down-regulating VEGF expression and suppression of TNF-α, IL-1β production.Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1.Origins of fibroblasts in rheumatoid synovial tissues: Implications from organ fibrotic models.Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.
P2860
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P2860
Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@en
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@nl
type
label
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@en
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@nl
prefLabel
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@en
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@nl
P2093
P2860
P356
P1433
P1476
Induction of the p16INK4a sene ...... tment of rheumatoid arthritis.
@en
P2093
Hirokawa K
Miyasaka N
Taniguchi K
P2860
P2888
P304
P356
10.1038/10480
P407
P577
1999-07-01T00:00:00Z
P6179
1030380784