Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.
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Concepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapiesChemo-immunotherapy with oxaliplatin and interleukin-7 inhibits colon cancer metastasis in miceNeoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice.Target-mediated disposition model describing the dynamics of IL12 and IFNγ after administration of a mifepristone-inducible adenoviral vector for IL-12 expression in mice.Safety profile of gutless adenovirus vectors delivered into the normal brain parenchyma: implications for a glioma phase 1 clinical trialImmunological off-target effects of standard treatments in gastrointestinal cancersThe relationship between the antitumor effect of the IL-12 gene therapy and the expression of Th1 cytokines in an HPV16-positive murine tumor model.The suppressive tumor microenvironment: a challenge in cancer immunotherapy.Cytokines for the treatment of gastrointestinal cancers: clinical experience and new perspectives.Hepatic myeloid-derived suppressor cells in cancer.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.Safety and antitumor effect of oncolytic and helper-dependent adenoviruses expressing interleukin-12 variants in a hamster pancreatic cancer model.Innate immune mediators in cancer: between defense and resistance.Hepatitis B virus reactivation in patients with solid tumors receiving systemic anticancer treatment.Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cells in vitro in a TLR4-independent mannerColon cancer eradication after chemoimmunotherapy is associated with intratumoral emergence of proinflammatory myeloid cells.Immunochemotherapy against colon cancer by gene transfer of interleukin-12 in combination with oxaliplatin.Enhancing immunotherapy using chemotherapy and radiation to modify the tumor microenvironment.Conditioning neoadjuvant therapies for improved immunotherapy of cancer.Re-designing Interleukin-12 to enhance its safety and potential as an anti-tumor immunotherapeutic agent.Chemotherapy ± cetuximab modulates peripheral immune responses in metastatic colorectal cancer.New trends in antitumor vaccines in melanoma.Improved anti-tumor efficacy via combination of oxaliplatin and fibrin glue in colorectal cancer.Interaction analysis of IL-12A and IL-12B polymorphisms with the risk of colorectal cancer.
P2860
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P2860
Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@en
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@nl
type
label
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@en
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@nl
prefLabel
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@en
Oxaliplatin in combination wit ...... tic colorectal cancer in mice.
@nl
P2093
P50
P356
P1433
P1476
Oxaliplatin in combination wit ...... atic colorectal cancer in mice
@en
P2093
Gloria Gonzalez-Aseguinolaza
Itsaso Mauleon
Jose Medina-Echeverz
Julien Crettaz
Manuela Gonzalez-Aparicio
Pedro Berraondo
Pilar Alzuguren
Ruben Hernandez-Alcoceba
P304
P356
10.1136/GUT.2010.211722
P407
P577
2010-09-20T00:00:00Z