Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Retention behavior of flavonoids on immobilized artificial membrane chromatography and correlation with cell-based permeability.

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P2860

Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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P2860

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Guidance for robustness/ruggedness tests in method validation

Current methodologies used for evaluation of intestinal permeability and absorption.

Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution.

Role of Caco-2 cell monolayers in prediction of intestinal drug absorption.

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells.

Strategies for absorption screening in drug discovery and development.

Assessing the absorption of new pharmaceuticals.

Application of hydrogen bonding calculations in property based drug design.

Separation methods for estimating octanol-water partition coefficients.

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175-183

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10.1093/CHROMSCI/BMR044

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Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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P2860

P2860

Orthogonal chromatographic descriptors for modelling Caco-2 drug permeability.

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