Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver.
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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectorsGenetic heterogeneity in response to adenovirus gene therapyPharmacogenetic heterogeneity of transgene expression in muscle and tumoursCombined bacterial and viral treatment: a novel anticancer strategySPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131IAdenovirus-mediated gene expression imaging to directly detect sentinel lymph node metastasis of prostate cancer.Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors.Expanded anticancer therapeutic window of hexon-modified oncolytic adenovirus.Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene TherapyOptimization of adenoviral vectors to direct highly amplified prostate-specific expression for imaging and gene therapy.The influence of innate and pre-existing immunity on adenovirus therapyEfficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primatesRedundant and synergistic mechanisms control the sequestration of blood-born adenovirus in the liver.Hepatic gene transfer as a means of tolerance induction to transgene productsIntensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesReducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactionsOncolytic viruses: From bench to bedside with a focus on safety.Recognition of virus infection and innate host responses to viral gene therapy vectors.Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.Molecular analysis of vector genome structures after liver transduction by conventional and self-complementary adeno-associated viral serotype vectors in murine and nonhuman primate modelsEncapsulation of adenovirus serotype 5 in anionic lecithin liposomes using a bead-based immunoprecipitation technique enhances transfection efficiency.Evaluation of innate immunity and vector toxicity following inoculation of bovine, porcine or human adenoviral vectors in a mouse modelDevelopment of a novel helper-dependent adenovirus-Epstein-Barr virus hybrid system for the stable transformation of mammalian cells.Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectorsRole of RGD-containing ligands in targeting cellular integrins: Applications for ovarian cancer virotherapy (Review)Head and neck cancer: gene therapy approaches. Part 1: adenoviral vectors.Delivery of an EBV episome by a self-circularizing helper-dependent adenovirus: long-term transgene expression in immunocompetent mice.Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complementChapter two--Adenovirus strategies for tissue-specific targeting.Mutation of the fiber shaft heparan sulphate binding site of a 5/3 chimeric adenovirus reduces liver tropism.Adenovirus vector induced innate immune responses: impact upon efficacy and toxicity in gene therapy and vaccine applications.Species differences in the pharmacology and toxicology of PEGylated helper-dependent adenovirusHelper-dependent adenoviral vectors for liver-directed gene therapy.Rapamycin enhances adenovirus-mediated cancer imaging and therapy in pre-immunized murine hostsReplicating parvoviruses that target colon cancer cellsIntravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma modelA potential role of distinctively delayed blood clearance of recombinant adeno-associated virus serotype 9 in robust cardiac transduction.Transient depletion of kupffer cells leads to enhanced transgene expression in rat liver following retrograde intrabiliary infusion of plasmid DNA and DNA nanoparticles.Impact of natural IgM concentration on gene therapy with adenovirus type 5 vectors.In vivo image analysis of BoHV-4-based vector in mice.
P2860
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P2860
Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Sequestration of adenoviral ve ...... onse of transduction in liver.
@en
Sequestration of adenoviral ve ...... onse of transduction in liver.
@nl
type
label
Sequestration of adenoviral ve ...... onse of transduction in liver.
@en
Sequestration of adenoviral ve ...... onse of transduction in liver.
@nl
prefLabel
Sequestration of adenoviral ve ...... onse of transduction in liver.
@en
Sequestration of adenoviral ve ...... onse of transduction in liver.
@nl
P2093
P356
P1433
P1476
Sequestration of adenoviral ve ...... onse of transduction in liver.
@en
P2093
Johnston J
P356
10.1006/MTHE.2000.0227
P577
2001-01-01T00:00:00Z