Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates - Wikidata - wikimedia - TriplyDB

Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates

Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates

http://www.wikidata.org/entity/Q33713289

about

Gene Therapy for Metabolic Diseases Adenoviral Vectors for Hemophilia Gene Therapy Strategies to modulate immune responses: a new frontier for gene therapy MyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus.Gene transfer into rat brain using adenoviral vectors.Vasoactive intestinal peptide increases hepatic transduction and reduces innate immune response following administration of helper-dependent Ad.Safety assessment of liver-targeted hydrodynamic gene delivery in dogs.Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Helper-dependent adenoviral vectors are superior in vitro to first-generation vectors for endothelial cell-targeted gene therapy.Correction of hyperbilirubinemia in gunn rats using clinically relevant low doses of helper-dependent adenoviral vectors Gene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector.Helper-dependent adenoviral vectors for liver-directed gene therapy.Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries Helper-dependent adenoviral vector achieves prolonged, stable expression of interleukin-10 in rabbit carotid arteries but does not limit early atherogenesis SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction.NOD2 signaling contributes to the innate immune response against helper-dependent adenovirus vectors independently of MyD88 in vivo.Reduction of ethanol consumption in alcohol-preferring rats by dual expression gene transfer Balloon catheter delivery of helper-dependent adenoviral vector results in sustained, therapeutic hFIX expression in rhesus macaques.Differential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs. adeno-associated viral vectors in vivo.Liver transplantation for classical maple syrup urine disease: long-term follow-up in 37 patients and comparative United Network for Organ Sharing experience Transgene expression up to 7 years in nonhuman primates following hepatic transduction with helper-dependent adenoviral vectors.Helper-Dependent Adenoviral Vectors.The role of liver sinusoidal cells in hepatocyte-directed gene transfer.AAV-mediated gene therapy for liver diseases: the prime candidate for clinical application?Gene therapy for haemophilia: a long and winding road.Gene therapy with helper-dependent adenoviral vectors: current advances and future perspectives.Recent advances in developing nucleic acid-based HBV therapy.Helper-dependent adenoviral vectors for liver-directed gene therapy of primary hyperoxaluria type 1.Recent advances in gene therapy for lysosomal storage disorders.Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus.Gene therapy with helper-dependent adenoviral vectors: lessons from studies in large animal models.Short-term correction of arginase deficiency in a neonatal murine model with a helper-dependent adenoviral vector.A Novel Adenoviral Hybrid-vector System Carrying a Plasmid Replicon for Safe and Efficient Cell and Gene Therapeutic Applications.Gene transfer of master autophagy regulator TFEB results in clearance of toxic protein and correction of hepatic disease in alpha-1-anti-trypsin deficiency.High-level production of replication-defective human immunodeficiency type 1 virus vector particles using helper-dependent adenovirus vectors.Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression.Efficient liver gene transfer with foamy virus vectors.Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.Advances in Overcoming Immune Responses following Hemophilia Gene Therapy.

P2860

Q28595868-15EE605E-2681-498C-96D6-7762EE1D7CF2 Q33690648-A2CCD8AF-9040-4B7F-A926-B45EDCA287D3 Q33713999-0AA95E7F-9EAD-445F-BA2E-C494F33BAB11 Q33832157-DD653883-C139-4F4F-B83E-974C1C5CAFFC Q33904294-A2A166FE-5DD4-4475-AA58-D75E4C25241E Q34025143-73E96081-E360-4479-AF58-A8A71B4DFD80 Q34245692-E1D656BF-460C-4B17-B765-D99FDBC89CA9 Q34343757-BFC6B974-A44E-412F-9547-6E325220F81F Q34382972-27B09038-DC70-4E8A-9108-B39C17B677E5 Q34774816-7825C274-FCCD-4AF2-BD75-ABC2F4CB71FE Q34892789-261EF65B-8781-4FE5-8A33-C7B666553317 Q34982825-A545014A-24C4-444A-A848-D9091E700E8D Q34993431-F5C715E2-E1C8-4C23-88EC-4E0ABA64B0E7 Q35174913-A7372852-4A60-4CE3-8AD4-B07E8B3F3CAF Q35224065-73EAC3F7-A732-4C49-8497-72B6B6CCFC30 Q35226121-CFCA5FD7-5C70-4EA5-973F-5BD9893827A6 Q35772588-A01D4334-9EB6-4451-B1AF-11DC18DEE02D Q36298627-0A998CAE-9ED3-45EC-8DE9-42F5222E4BD2 Q36740271-A918A2B7-7D82-46F6-9BF9-0DAB919FCA80 Q36900920-B79C521A-EC79-4598-986B-8927C96BC873 Q37102059-651CFAB7-C49B-4CAB-BA75-867276E0B919 Q37582126-F7CD8E1D-9523-4EAB-9E93-C52B9CEBC652 Q37641568-42642190-CAEB-42E3-B80E-0DF2553668CD Q37825907-18DF2784-F882-4446-B1C0-FE4E28997412 Q37903924-6CBFECC5-3752-4329-8C1E-D22AEF62C3ED Q37945218-8BEFBC64-00E9-4863-9317-B8DEF5EDE67E Q38160538-E0D33050-9B52-4B0D-B595-D0506D90607D Q38302375-A6D35965-4039-46F4-8F07-BD57C7E28574 Q38546492-00284F21-53A8-456C-9AD5-1A5B2B16F30F Q38647828-421616FE-B92A-4FAF-BA05-36A301CAFD00 Q38846270-85371E57-FD78-4025-9094-BCAD9454CC11 Q39358889-25D64429-8443-4C2A-BB1F-7D101373283E Q39508670-929C9E26-D19F-4B23-9312-09AEB30DD9E1 Q40596293-636DF6EB-5E56-4D0F-A07A-483FAFF4C86C Q41106554-59DAA769-FF32-4062-BBC6-A0CB3F7DC70F Q41124092-9B16C1C1-E058-44DF-B8E1-47B1D49EA31F Q41627013-6590D296-B151-4C01-B627-B2F14B89A254 Q42054773-04E0E440-03C8-4165-ACA1-5CC5149058BC Q42204796-92CAE633-8938-43E1-83E2-CEAA278A2EA3 Q42209182-8B92E7A0-5E16-4E84-B058-CBE4223057A5

P2860

Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primates

http://www.wikidata.org/entity/Q33713289

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@ast

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@en

type

label

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@ast

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@en

prefLabel

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@ast

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@en

P1433

Q33713289-E1A69FEE-34BC-4E25-A878-71B66A6FC368

P1476

Q33713289-337A6F91-53AF-4100-BE04-B93A547C4A07

P2093

Q33713289-075EED77-C326-4BD4-8B80-0097400D743F

Q33713289-32A02D3E-127A-466D-A7BC-FE2DC7C9BCA8

Q33713289-39F13AD9-5B2C-48C2-BABF-544B04261A77

Q33713289-4F5BD26E-1520-43BD-B3E7-B7CFF478C963

Q33713289-6B4022B9-F85E-4DC8-91FE-1A2D12213169

Q33713289-6F6662BC-1DBD-404C-AE84-FB12F3934CD6

Q33713289-B81D406B-23F1-4193-9993-5ED06FE5916B

Q33713289-C042307F-D7E8-4DFA-9F36-56F15284D3A0

Q33713289-C92A706C-BB46-4980-A802-96F07BA48A8F

Q33713289-DB7D0C0B-A54C-4B9D-8E92-EE67584AC457

P2860

Q33713289-07510C25-6A3F-45C6-8FF6-AC8B800200AE

Q33713289-0F13C031-57AC-4FA4-A988-26A40D5F91AC

Q33713289-101BC445-B737-4621-ABD5-0AACDD4C1C44

Q33713289-1E2AE125-FCB2-4980-9DA0-3C467E5EE8BD

Q33713289-431A3340-B0D7-4327-8510-5B0DFF090F61

Q33713289-4C8D798C-415A-4B51-A7D9-C2728F76EDBD

Q33713289-5F257D73-E586-4832-B3A7-7584F95F3EE7

Q33713289-72FB392F-7D81-4F7D-B5B2-6FAAC283A578

Q33713289-7488616D-2A7F-45B8-9975-E39503A4F914

Q33713289-7A850544-D43F-4C7D-8888-0609E72ED77D

P304

Q33713289-9A4FB324-2688-42D3-9723-F152D198AEB0

P31

Q33713289-654C0C52-4AD0-4678-8F46-3F5FD877E8CE

P356

Q33713289-244A058F-261B-4DF1-95BF-28EED5DA65A5

P433

Q33713289-BF77296A-542A-4DB8-B36C-78F9D8C35189

P478

Q33713289-8322E328-924E-44A2-93D9-3D1898F16A1D

P577

Q33713289-9AAD0AC8-C1D2-43D8-A80A-96646919782A

P5875

Q33713289-0303449D-49C6-473E-9C88-0C86D6AB61B9

P698

Q33713289-99F91DF5-F3E1-46C4-A09E-AF6538FF47AA

P921

Q33713289-8F0698D7-2772-4CE9-8141-419922976778

P932

Q33713289-787A56E1-D288-4022-800C-0D2E2816626D

P356

P1433

Molecular Therapy

P1476

Efficient, long-term hepatic g ...... delivery in nonhuman primates

@en

P2093

Arthur L Beaudet

http://www.w3.org/2001/XMLSchema#string

Charles E Mullins

http://www.w3.org/2001/XMLSchema#string

Donna J Palmer

http://www.w3.org/2001/XMLSchema#string

Gary E Stapleton

http://www.w3.org/2001/XMLSchema#string

John Breinholt

http://www.w3.org/2001/XMLSchema#string

Karen Rice

http://www.w3.org/2001/XMLSchema#string

Mark Law

http://www.w3.org/2001/XMLSchema#string

Milton J Finegold

http://www.w3.org/2001/XMLSchema#string

Nathan C Grove

http://www.w3.org/2001/XMLSchema#string

Nicola Brunetti-Pierri

http://www.w3.org/2001/XMLSchema#string

P2860

Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons.

A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.

Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery.

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung

Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

Preexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicity.

Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

P304

327-333

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/MT.2008.257

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P577

2008-12-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23563736

http://www.w3.org/2001/XMLSchema#string

P698

19050700

http://www.w3.org/2001/XMLSchema#string

P921

catheterization

P932

2835071

http://www.w3.org/2001/XMLSchema#string