A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP.
about
Transplantation Tolerance Induction: Cell Therapies and Their MechanismsCell therapy to induce allograft tolerance: time to switch to plan B?B-cell delivered gene therapy for tolerance induction: role of autoantigen-specific B cells.Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se.Inhibitors - cellular aspects and novel approaches for tolerance.Development of Gene Transfer for Induction of Antigen-specific Tolerance.B-Cell Gene Therapy for Tolerance Induction: Host but Not Donor B-Cell Derived IL-10 is Necessary for Tolerance.B cells "transduced" with TAT-fusion proteins can induce tolerance and protect mice from diabetes and EAECytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosisReprogrammed quiescent B cells provide an effective cellular therapy against chronic experimental autoimmune encephalomyelitis.Antigen-specific therapies in multiple sclerosis.B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathwayAdvances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy.In vivo reprogramming of immune cells: Technologies for induction of antigen-specific tolerance.High Efficiency Ex Vivo Gene Transfer to Primary Murine B Cells Using Plasmid or Viral VectorsInduction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins.Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.B-cell-delivered gene therapy induces functional T regulatory cells and leads to a loss of antigen-specific effector cells.Prevention of murine experimental autoimmune encephalomyelitis by in vivo expression of a novel recombinant immunotoxin DT390-RANTES.Transduced B cells: B is for 'beneficial'!From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance.
P2860
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P2860
A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP.
description
2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@en
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@nl
type
label
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@en
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@nl
prefLabel
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@en
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@nl
P921
P1433
P1476
A novel retroviral gene therap ...... elitis induced by MOG and MBP.
@en
P2093
David W Scott
P356
10.1016/J.CLIM.2003.12.013
P577
2004-04-01T00:00:00Z