Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo.
about
Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancerMicroRNAs of the mir-17~92 cluster regulate multiple aspects of pancreatic tumor development and progression.Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growthα-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model.Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancerOpposite effects of tissue inhibitor of metalloproteinases-1 (TIMP-1) over-expression and knockdown on colorectal liver metastases.Prediction of metalloproteinase family based on the concept of Chou's pseudo amino acid composition using a machine learning approach.Gene therapy in pancreatic cancer.Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus.Novel perspective: focusing on the X chromosome in reproductive cancers.Gene transfer: Bax to the future for cancer therapy.Loss of Endothelial Barrier in Marfan Mice (mgR/mgR) Results in Severe Inflammation after Adenoviral Gene TherapyNew pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster.Invasion of normal human fibroblasts induced by v-Fos is independent of proliferation, immortalization, and the tumor suppressors p16INK4a and p53.ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.Hematopoiesis in mice is extremely resilient to wide variation in TIMP/MMP balance.Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.TIMP-1 and CD82, a promising combined evaluation marker for PDAC.MiR-301a promotes cell proliferation by directly targeting TIMP2 in multiple myeloma.Invasive potential of melanoma cells correlates with the expression of MT1-MMP and regulated by modulating its association with motility receptors via N-glycosylation on the receptors.Gene Therapy for Pancreatic Cancer: Specificity, Issues and Hopes.Tissue inhibitor of matrix metalloproteinase-1 overexpression in M1 myeloblasts impairs IL-6-induced differentiation.AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo.Tissue inhibitor of metalloproteinase 2 inhibits activation of the β-catenin signaling in melanoma cells.Current diagnostics and treatment of fibrosarcoma -perspectives for future therapeutic targets and strategies.
P2860
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P2860
Adenoviral delivery of TIMP1 or TIMP2 can modify the invasive behavior of pancreatic cancer and can have a significant antitumor effect in vivo.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@en
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@nl
type
label
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@en
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@nl
prefLabel
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@en
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@nl
P356
P1433
P1476
Adenoviral delivery of TIMP1 o ...... cant antitumor effect in vivo.
@en
P2093
P2888
P304
P356
10.1038/SJ.CGT.7700387
P577
2001-11-01T00:00:00Z
P5875
P6179
1013400535