Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat.
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Gene therapy for lipid disordersAdenoviral vector immunity: its implications and circumvention strategies.Strategies to modulate immune responses: a new frontier for gene therapyGene therapy of hepatic diseases: prospects for the new millennium.Intensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesCurrent strategies and future directions for eluding adenoviral vector immunityEncapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response.Repeated adenoviral administration into the biliary tract can induce repeated expression of the original gene construct in rat livers without immunosuppressive strategies.Liver gene therapy: advances and hurdles.Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.NF-κB promotes leaky expression of adenovirus genes in a replication-incompetent adenovirus vector.A mouse model of inducible liver injury caused by tet-on regulated urokinase for studies of hepatocyte transplantation.Biology of E1-deleted adenovirus vectors in nonhuman primate muscle.A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome.The prospects of hepatic drug delivery and gene therapy.Immunomodulation of experimental colitis: the role of NK1.1 liver lymphocytes and surrogate antigens--bystander effect.Long-term normalization in the central nervous system, ocular manifestations, and skeletal deformities by a single systemic adenovirus injection into neonatal mice with mucopolysaccharidosis VII.Role of NK1.1+ and AsGm-1+ cells in oral immunoregulation of experimental colitis.Adoptive transfer of ex vivo immune-programmed NKT lymphocytes alleviates immune-mediated colitis.Inducing oral immune regulation of hepatitis B virus envelope proteins suppresses the growth of hepatocellular carcinoma in mice.Transient cyclophosphamide treatment before intraportal readministration of an adenoviral vector can induce re-expression of the original gene construct in rat liver.Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies.
P2860
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P2860
Transient immunosuppression with FK506 permits long-term expression of therapeutic genes introduced into the liver using recombinant adenoviruses in the rat.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
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1997年学术文章
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1997年学术文章
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1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
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1997年學術文章
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1997年學術文章
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name
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@en
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@nl
type
label
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@en
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@nl
prefLabel
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@en
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@nl
P2093
P356
P1433
P1476
Transient immunosuppression wi ...... inant adenoviruses in the rat.
@en
P2093
Horwitz MS
Roy-Chowdhury J
Roy-Chowdhury N
Sengupta K
P304
P356
10.1002/HEP.510260422
P407
P577
1997-10-01T00:00:00Z