Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.
about
A transposon and transposase system for human applicationComparative analysis of transposable element vector systems in human cellsPreferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injectionAnti-angiogenic gene therapy in the treatment of malignant gliomasInternal ribosome entry site-based vectors for combined gene therapyMouse models of cancer: Sleeping Beauty transposons for insertional mutagenesis screens and reverse genetic studiesDNA transposon-based gene vehicles - scenes from an evolutionary driveShielding of sleeping beauty DNA transposon-delivered transgene cassettes by heterologous insulators in early embryonal cellsPhase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adultsPhase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.Tumor-directed gene therapy in mice using a composite nonviral gene delivery system consisting of the piggyBac transposon and polyethylenimine.Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons.Role of type 1 IFNs in antiglioma immunosurveillance--using mouse studies to guide examination of novel prognostic markers in humans.Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.Macrophages homing to metastatic lymph nodes can be monitored with ultrasensitive ferromagnetic iron-oxide nanocubes and a 1.5T clinical MR scanner.Therapeutic efficacy of aldoxorubicin in an intracranial xenograft mouse model of human glioblastoma.Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon SystemTopical imiquimod has therapeutic and immunomodulatory effects against intracranial tumorsGene therapy for cancer treatment: past, present and futureComparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells.Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigationType I collagen gene suppresses tumor growth and invasion of malignant human glioma cellsDecreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma.Retargeting transposon insertions by the adeno-associated virus Rep protein.Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy.Sleeping Beauty transposon system for genetic etiological research and gene therapy of cancers.A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA TransposonReview: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions.Convection-enhanced delivery in the treatment of malignant glioma.Morphine induces splenocyte trafficking into the CNS.Efficacy of nonviral gene transfer in the canine brain.Improved distribution of small molecules and viral vectors in the murine brain using a hollow fiber catheter.Noninvasive molecular neuroimaging using reporter genes: part II, experimental, current, and future applications.Blood outgrowth endothelial cell-based systemic delivery of antiangiogenic gene therapy for solid tumors.De novo induction of genetically engineered brain tumors in mice using plasmid DNANano to micro delivery systems: targeting angiogenesis in brain tumors.The expanding universe of transposon technologies for gene and cell engineering.The Sleeping Beauty transposon system for clinical applications.Recent developments in transposon-mediated gene therapy.Sleeping Beauty transposition: from biology to applications.
P2860
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P2860
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@en
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@nl
type
label
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@en
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@nl
prefLabel
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@en
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@nl
P2093
P1433
P1476
Combinatorial antiangiogenic g ...... tracranial human glioblastoma.
@en
P2093
Andrew B Freese
David A Largaespada
Eleanor Chen
Frank A Scappaticci
Isabelita Vengco
John R Ohlfest
Rachel J Saplis
Seunguk Oh
Stephen C Ekker
Walter C Low
P304
P356
10.1016/J.YMTHE.2005.07.689
P577
2005-09-16T00:00:00Z