Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

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Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer.The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity.Small molecule KDM4s inhibitors as anti-cancer agents.

P2860

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P2860

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

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http://www.wikidata.org/entity/Q45948669

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@en

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@nl

type

Item

label

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@en

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@nl

prefLabel

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@en

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@nl

P1476

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

@en

P2093

Alessandro Cuomo

http://www.w3.org/2001/XMLSchema#string

Andrew McGeehan

http://www.w3.org/2001/XMLSchema#string

Chon Lai

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David J Hosfield

http://www.w3.org/2001/XMLSchema#string

James M Veal

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Stafford

http://www.w3.org/2001/XMLSchema#string

Jennifer Matuszkiewicz

http://www.w3.org/2001/XMLSchema#string

Joselyn R Del Rosario

http://www.w3.org/2001/XMLSchema#string

Lihong Shi

http://www.w3.org/2001/XMLSchema#string

Michael B Wallace

http://www.w3.org/2001/XMLSchema#string

P2860

Histone demethylases in chromatin biology and beyond

Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and prevention

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives

Chromatin modifications and their function

Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

P304

869-874

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scholarly article

P356

10.1021/ACSMEDCHEMLETT.7B00220

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Tiziana Bonaldi

P577

2017-07-27T00:00:00Z

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28835804

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P932

5554903

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Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

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P2860

P2860

Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932