Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.

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Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel

P2860

Q57821196-F024CE5B-BF94-48B9-B0F3-9AF7B10296CA

P2860

Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.

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http://www.wikidata.org/entity/Q45952614

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Identification of Potent and S ...... ment of Inflammatory Diseases.

@en

Identification of Potent and S ...... ment of Inflammatory Diseases.

@nl

type

Item

label

Identification of Potent and S ...... ment of Inflammatory Diseases.

@en

Identification of Potent and S ...... ment of Inflammatory Diseases.

@nl

prefLabel

Identification of Potent and S ...... ment of Inflammatory Diseases.

@en

Identification of Potent and S ...... ment of Inflammatory Diseases.

@nl

P1476

Identification of Potent and S ...... ment of Inflammatory Diseases.

@en

P2093

Badry Bursulaya

http://www.w3.org/2001/XMLSchema#string

Barun Okram

http://www.w3.org/2001/XMLSchema#string

Bo Liu

http://www.w3.org/2001/XMLSchema#string

David Huang

http://www.w3.org/2001/XMLSchema#string

Glen Spraggon

http://www.w3.org/2001/XMLSchema#string

Hong Liu

http://www.w3.org/2001/XMLSchema#string

Janine Baaten

http://www.w3.org/2001/XMLSchema#string

Jian Shi

http://www.w3.org/2001/XMLSchema#string

John Fathman

http://www.w3.org/2001/XMLSchema#string

John Nelson

http://www.w3.org/2001/XMLSchema#string

P2860

RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis

Profile-QSAR: a novel meta-QSAR method that combines activities across the kinase family to accurately predict affinity, selectivity, and cellular activity.

Bioavailability challenges associated with development of anti-cancer phenolics.

Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan

Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses.

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity.

Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis.

P304

1048-1053

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.7B00258

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Andreas Kreusch

P577

2017-09-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29057049

http://www.w3.org/2001/XMLSchema#string

P932

5641954

http://www.w3.org/2001/XMLSchema#string

Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.

about

P2860

P2860

Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932