A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.
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Gelatinase B/MMP-9 in Tumour Pathogenesis and ProgressionMatrix metalloproteinases in exercise and obesityOxidative DNA Damage Mediated by Intranuclear MMP Activity Is Associated with Neuronal Apoptosis in Ischemic StrokeDIDS prevents ischemic membrane degradation in cultured hippocampal neurons by inhibiting matrix metalloproteinase releaseEarly Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature MouseNeuroinflammation and cerebrovascular disease in old age: a translational medicine perspectiveSelective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injuryTwo-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuriesDelayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental strokeMyocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cellsPharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular diseaseMatrix metalloproteinases and the regulation of tissue remodellingSystemic expression of matrix metalloproteinase-9 in patients with cerebral arteriovenous malformations.Doxycycline treatment decreases morbidity and mortality of murine neurocysticercosis: evidence for reduction of apoptosis and matrix metalloproteinase activity.The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humansVariants of the Matrix Metalloproteinase-2 but not the Matrix Metalloproteinase-9 genes significantly influence functional outcome after stroke.Ectoplasmic specialization: a friend or a foe of spermatogenesis?TNF alpha-mediated disruption of spermatogenesis in response to Sertoli cell injury in rodents is partially regulated by MMP2Neuroprotective effects of overexpressing tissue inhibitor of metalloproteinase TIMP-1.Human umbilical cord blood cell therapy blocks the morphological change and recruitment of CD11b-expressing, isolectin-binding proinflammatory cells after middle cerebral artery occlusion.Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases.Matrix metalloproteinases, T cell homing and beta-cell mass in type 1 diabetes.p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9.MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage.Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity.MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat.Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors.The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration.The dual role of the neuroinflammatory response after ischemic stroke: modulatory effects of hypothermia.β1 integrin-focal adhesion kinase (FAK) signaling modulates retinal ganglion cell (RGC) survival.Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.Ischemic postconditioning decreases cerebral edema and brain blood barrier disruption caused by relief of carotid stenosis in a rat model of cerebral hypoperfusionOxidative stress in ischemic brain damage: mechanisms of cell death and potential molecular targets for neuroprotectionRole of matrix metalloproteinases and therapeutic benefits of their inhibition in spinal cord injury.Exploration of mild copper-mediated coupling of organotrifluoroborates in the synthesis of thiirane-based inhibitors of matrix metalloproteinasesWhite matter damage and the effect of matrix metalloproteinases in type 2 diabetic mice after stroke.Association between the MMP-9-1562 C>T polymorphism and the risk of stroke: a meta-analysis.Matrix metalloproteinase-9 controls proliferation of NG2+ progenitor cells immediately after spinal cord injury.A gene expression-based comparison of cell adhesion to extracellular matrix and RGD-terminated monolayers.Selective water-soluble gelatinase inhibitor prodrugs.
P2860
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P2860
A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@en
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@nl
type
label
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@en
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@nl
prefLabel
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@en
A highly specific inhibitor of ...... sient focal cerebral ischemia.
@nl
P2093
P1476
A highly specific inhibitor of ...... nsient focal cerebral ischemia
@en
P2093
Jiankun Cui
Rafael Fridman
Shahriar Mobashery
Stephen Brown
Stuart A Lipton
P304
P356
10.1523/JNEUROSCI.1563-05.2005
P407
P577
2005-07-01T00:00:00Z