about
A urokinase receptor-associated protein with specific collagen binding propertiesFibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradationThe collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion bindingNo effect of NGAL/lipocalin-2 on aggressiveness of cancer in the MMTV-PyMT/FVB/N mouse model for breast cancerM2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.Differential gene expression in human mammary carcinoma cells: identification of a new member of a receptor family.Gender affects skin wound healing in plasminogen deficient mice.Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasisLoss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female miceThe non-phagocytic route of collagen uptake: a distinct degradation pathway.Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion.Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesisC4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes.Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programsMT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.The collagen receptor uPARAP/Endo180.Complex determinants in specific members of the mannose receptor family govern collagen endocytosisThe focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion.Advances in targeted delivery of small interfering RNA using simple bioconjugates.Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells.A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor.The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy.Identification of two estrogen regulated genes associated with growth regulation of human breast cancer.uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner.Quantification of tissue inhibitor of metalloproteinases 2 in plasma from healthy donors and cancer patients.CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1-Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma.Differential binding of urokinase and peptide antagonists to the urokinase receptor: evidence from characterization of the receptor in four primate species.Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.Monitoring mammary tumor progression and effect of tamoxifen treatment in MMTV-PymT using MRI and magnetic resonance spectroscopy with hyperpolarized [1-13C]pyruvateTargeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectinsIncreased Expression of the Collagen Internalization Receptor uPARAP/Endo180 in the Stroma of Head and Neck Cancer
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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Lars Henning Engelholm
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P106
P21
P31
P496
0000-0002-6616-1232