Pim-1 regulates cardiomyocyte survival downstream of Akt.
about
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancersEnhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinaseSuppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac DysfunctionIs REDD1 a Metabolic Éminence Grise?The PIM kinases in hematological cancersHyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation.Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1Imaging survival and function of transplanted cardiac resident stem cellsOrai1 deficiency leads to heart failure and skeletal myopathy in zebrafishCardiac stem cell therapy for cardiac repair.Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyteRapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathwayMechanistic target of rapamycin complex 2 protects the heart from ischemic damageCell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.Empowering adult stem cells for myocardial regenerationPreservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cellsPhosphoprotein abundance changes in hypertensive cardiac remodeling.Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.Metabolic dysfunction consistent with premature aging results from deletion of Pim kinasesCardiac progenitor cell commitment is inhibited by nuclear Akt expression.Cardiac progenitor cell cycling stimulated by pim-1 kinaseMitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis.EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferationCardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules.Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells.Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPKcJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activationThe antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunctionEnhancing the potential of cardiac progenitor cells: pushing forward with Pim-1.Cell-based therapy for prevention and reversal of myocardial remodelingPIM1-minicircle as a therapeutic treatment for myocardial infarction.In search of new therapeutic targets and strategies for heart failure: recent advances in basic scienceCardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes.Diabetic cardiomyopathy and metabolic remodeling of the heart.Mechanisms of disease: detrimental adrenergic signaling in acute decompensated heart failure.Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation.microRNA-206 is involved in survival of hypoxia preconditioned mesenchymal stem cells through targeting Pim-1 kinase.
P2860
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P2860
Pim-1 regulates cardiomyocyte survival downstream of Akt.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@en
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@nl
type
label
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@en
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@nl
prefLabel
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@en
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@nl
P2093
P2860
P50
P356
P1433
P1476
Pim-1 regulates cardiomyocyte survival downstream of Akt.
@en
P2093
Annarosa Leri
Anton Berns
Christopher C Glembotski
Christopher Cottage
Erik M Schaefer
Francesca Delucchi
Grazia Esposito
Gregory N Emmanuel
Jan Kajstura
Jenna Fransioli
P2860
P2888
P304
P356
10.1038/NM1671
P407
P577
2007-11-25T00:00:00Z