Pim-1 regulates cardiomyocyte survival downstream of Akt. - Wikidata - wikimedia - TriplyDB

Pim-1 regulates cardiomyocyte survival downstream of Akt.

Pim-1 regulates cardiomyocyte survival downstream of Akt.

http://www.wikidata.org/entity/Q46022665

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PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction Is REDD1 a Metabolic Éminence Grise?The PIM kinases in hematological cancers Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation.Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1 Imaging survival and function of transplanted cardiac resident stem cells Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish Cardiac stem cell therapy for cardiac repair.Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1 Pim-1 kinase protects mitochondrial integrity in cardiomyocytes.Vitamin B1 analog benfotiamine prevents diabetes-induced diastolic dysfunction and heart failure through Akt/Pim-1-mediated survival pathway Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase.Activation of cell cycle arrest and apoptosis by the proto-oncogene Pim-2.Empowering adult stem cells for myocardial regeneration Preservation of myocardial structure is enhanced by pim-1 engineering of bone marrow cells Phosphoprotein abundance changes in hypertensive cardiac remodeling.Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases Cardiac progenitor cell commitment is inhibited by nuclear Akt expression.Cardiac progenitor cell cycling stimulated by pim-1 kinase Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis.EBNA3C augments Pim-1 mediated phosphorylation and degradation of p21 to promote B-cell proliferation Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules.Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells.Transient activation of p38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction Enhancing the potential of cardiac progenitor cells: pushing forward with Pim-1.Cell-based therapy for prevention and reversal of myocardial remodeling PIM1-minicircle as a therapeutic treatment for myocardial infarction.In search of new therapeutic targets and strategies for heart failure: recent advances in basic science Cardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes.Diabetic cardiomyopathy and metabolic remodeling of the heart.Mechanisms of disease: detrimental adrenergic signaling in acute decompensated heart failure.Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation.microRNA-206 is involved in survival of hypoxia preconditioned mesenchymal stem cells through targeting Pim-1 kinase.

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Pim-1 regulates cardiomyocyte survival downstream of Akt.

http://www.wikidata.org/entity/Q46022665

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2007年學術文章

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name

Pim-1 regulates cardiomyocyte survival downstream of Akt.

@en

Pim-1 regulates cardiomyocyte survival downstream of Akt.

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type

label

Pim-1 regulates cardiomyocyte survival downstream of Akt.

@en

Pim-1 regulates cardiomyocyte survival downstream of Akt.

@nl

prefLabel

Pim-1 regulates cardiomyocyte survival downstream of Akt.

@en

Pim-1 regulates cardiomyocyte survival downstream of Akt.

@nl

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Nature Medicine

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Pim-1 regulates cardiomyocyte survival downstream of Akt.

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Annarosa Leri

http://www.w3.org/2001/XMLSchema#string

Anton Berns

http://www.w3.org/2001/XMLSchema#string

Christopher C Glembotski

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Christopher Cottage

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Erik M Schaefer

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Francesca Delucchi

http://www.w3.org/2001/XMLSchema#string

Grazia Esposito

http://www.w3.org/2001/XMLSchema#string

Gregory N Emmanuel

http://www.w3.org/2001/XMLSchema#string

Jan Kajstura

http://www.w3.org/2001/XMLSchema#string

Jenna Fransioli

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P2860

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

Identification of heterochromatin protein 1 (HP1) as a phosphorylation target by Pim-1 kinase and the effect of phosphorylation on the transcriptional repression function of HP1(1)

Pim-1 associates with protein complexes necessary for mitosis

Regulation and function of IKK and IKK-related kinases

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload

The serine/threonine kinase Pim-1

Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice

Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants

Prolactin signaling to pim-1 expression: a role for phosphatidylinositol 3-kinase.

Structure and substrate specificity of the Pim-1 kinase.

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10.1038/NM1671

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12

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18037896

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