KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.
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Human T cell aging and the impact of persistent viral infectionsCellular senescence impact on immune cell fate and functionMolecular characterization of HCMV-specific immune responses: Parallels between CD8(+) T cells, CD4(+) T cells, and NK cellsSorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?T cell replicative senescence in human agingConvergence of Innate and Adaptive Immunity during Human AgingFunctionally Diverse NK-Like T Cells Are Effectors and Predictors of Successful AgingMechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infectionBlimp-1 homolog Hobit identifies effector-type lymphocytes in humansBioengineering T cells to target carbohydrate to treat opportunistic fungal infection.Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans.P27(Kip1), regulated by glycogen synthase kinase-3β, results in HMBA-induced differentiation of human gastric cancer cells.Memories that last forever: strategies for optimizing vaccine T-cell memory.p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival.Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.Human effector CD8+ T cells derived from naive rather than memory subsets possess superior traits for adoptive immunotherapy.Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells.Intersection of mTOR and STAT signaling in immunityReprogramming CD19-specific T cells with IL-21 signaling can improve adoptive immunotherapy of B-lineage malignancies.Epithelial adhesion molecules can inhibit HIV-1-specific CD8⁺ T-cell functionsPolyfunctional T cell responses in children in early stages of chronic Trypanosoma cruzi infection contrast with monofunctional responses of long-term infected adults.Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy.KLRG1+NKG2A+ CD8 T cells mediate protection and participate in memory responses during γ-herpesvirus infection.Characterization of an effective CTL response against HIV and SIV infections.Pathogen-induced inflammatory environment controls effector and memory CD8+ T cell differentiation.Consensus nomenclature for CD8(+) T cell phenotypes in cancerImmunosenescence of the CD8(+) T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls.IL-7Rαlow memory CD8+ T cells are significantly elevated in patients with systemic lupus erythematosus.Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ studyHCV monoinfection and HIV/HCV coinfection enhance T-cell immune senescence in injecting drug users early during infectionThe janus head of T cell aging - autoimmunity and immunodeficiency.Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.KLRG1 negatively regulates natural killer cell functions through the Akt pathway in individuals with chronic hepatitis C virus infection.Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5'-Monophosphate-Activated Protein KinaseAdoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.Inhibitory Receptor Expression Depends More Dominantly on Differentiation and Activation than "Exhaustion" of Human CD8 T Cells.
P2860
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P2860
KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
KLRG1 signaling induces defect ...... y differentiated CD8+ T cells.
@en
KLRG1 signaling induces defective Akt
@nl
type
label
KLRG1 signaling induces defect ...... y differentiated CD8+ T cells.
@en
KLRG1 signaling induces defective Akt
@nl
prefLabel
KLRG1 signaling induces defect ...... y differentiated CD8+ T cells.
@en
KLRG1 signaling induces defective Akt
@nl
P2093
P50
P1433
P1476
KLRG1 signaling induces defect ...... y differentiated CD8+ T cells.
@en
P2093
Arne N Akbar
Fiona J Plunkett
Hans-Peter Pircher
Joanne E Masters
Maria V D Soares
Ornella Franzese
Richard Macaulay
Rita I Azevedo
Sorena Kiani-Alikhan
Valentina Libri
P304
P356
10.1182/BLOOD-2009-01-199588
P407
P577
2009-04-30T00:00:00Z