A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.
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Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseTargeting New Candidate Genes by Small Molecules Approaching Neurodegenerative DiseasesParkinson's disease: animal models and dopaminergic cell vulnerabilityThe promise and perils of HDAC inhibitors in neurodegenerationCellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disordersChemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle.Molecular chaperones and protein folding as therapeutic targets in Parkinson's disease and other synucleinopathiesGrp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitisAmelioration of glucolipotoxicity-induced endoplasmic reticulum stress by a "chemical chaperone" in human THP-1 monocytes.Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma.Phenylbutyric acid suppresses protein accumulation-mediated ER stress in retrovirus-infected astrocytes and delays onset of paralysis in infected miceBeneficial Effects of Sodium Phenylbutyrate Administration during Infection with Salmonella enterica Serovar Typhimurium.Molecular chaperones and associated cellular clearance mechanisms against toxic protein conformers in Parkinson's disease.Parkinson's disease mouse models in translational research.Animal models of Parkinson's disease: a gateway to therapeutics?Underlying mechanisms and chemical/biochemical therapeutic approaches to ameliorate protein misfolding neurodegenerative diseases.Neuroprotection by Epigenetic Modulation in a Transgenic Model of Multiple System AtrophySEAP activity serves for demonstrating ER stress induction by glucolipotoxicity as well as testing ER stress inhibitory potential of therapeutic agents.Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease.Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin.Sodium 4-phenylbutyrate ameliorates the effects of cataract-causing mutant gammaD-crystallin in cultured cells.Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism.Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice.Neuroprotective Effects of Germinated Brown Rice in Rotenone-Induced Parkinson's-Like Disease Rats.Orally administered sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice.Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones
P2860
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P2860
A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@en
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@nl
type
label
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@en
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@nl
prefLabel
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@en
A chemical chaperone, sodium 4 ...... n A30P + A53T transgenic mice.
@nl
P2093
P1476
A chemical chaperone, sodium 4 ...... in A30P + A53T transgenic mice
@en
P2093
Kazuhiko Ono
Manabu Nakashima
Masaki Ikeda
Mitsuo Takahashi
Miyuki Ikemoto
Takeshi Kawarabayashi
Takuya Nishinakagawa
P304
P356
10.1016/J.PARKRELDIS.2009.03.002
P577
2009-04-03T00:00:00Z