TFIIH XPB mutants suggest a unified bacterial-like mechanism for promoter opening but not escape.
about
Promoter clearance by RNA polymerase IIParticipation of XPB/Ptr8p, a component of TFIIH, in nucleocytoplasmic transport of mRNA in fission yeast.Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening.Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formation.G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.Mechanistic and biological aspects of helicase action on damaged DNA.Newly identified CHO ERCC3/XPB mutations and phenotype characterization.A prehydrolysis state of an AAA+ ATPase supports transcription activation of an enhancer-dependent RNA polymeraseXPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.The TFIIB tip domain couples transcription initiation to events involved in RNA processingOrganization of an activator-bound RNA polymerase holoenzymeTorsion-mediated interaction between adjacent genesTripartite DNA Lesion Recognition and Verification by XPC, TFIIH, and XPA in Nucleotide Excision Repair.Real-time footprinting of DNA in the first kinetically significant intermediate in open complex formation by Escherichia coli RNA polymerase.Mediator-regulated transcription through the +1 nucleosomeARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activitiesA DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex.Modus operandi of the bacterial RNA polymerase containing the sigma54 promoter-specificity factor.Coupling sigma factor conformation to RNA polymerase reorganisation for DNA meltingComparative analysis of activator-Esigma54 complexes formed with nucleotide-metal fluoride analogues.Molecular insights into the recruitment of TFIIH to sites of DNA damageTrypanosoma brucei harbours a divergent XPB helicase paralogue that is specialized in nucleotide excision repair and conserved among kinetoplastid organisms.Structural basis of transcription initiation by RNA polymerase II.Late steps in the formation of E. coli RNA polymerase-lambda P R promoter open complexes: characterization of conformational changes by rapid [perturbant] upshift experiments.PIC Activation through Functional Interplay between Mediator and TFIIH.RNA polymerase motions during promoter melting.Engineered interfaces of an AAA+ ATPase reveal a new nucleotide-dependent coordination mechanismTFIIH is an elongation factor of RNA polymerase I.A common feature from different subunits of a homomeric AAA+ protein contacts three spatially distinct transcription elements.The role of the conserved phenylalanine in the sigma54-interacting GAFTGA motif of bacterial enhancer binding proteins.Mechanism of transcription initiation at an activator-dependent promoter defined by single-molecule observation.Single-stranded DNA binding activity of XPBI, but not XPBII, from Sulfolobus tokodaii causes double-stranded DNA melting.An intramolecular route for coupling ATPase activity in AAA+ proteins for transcription activation.Structures of transcription pre-initiation complex with TFIIH and Mediator.Sensor I threonine of the AAA+ ATPase transcriptional activator PspF is involved in coupling nucleotide triphosphate hydrolysis to the restructuring of sigma 54-RNA polymerase.
P2860
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P2860
TFIIH XPB mutants suggest a unified bacterial-like mechanism for promoter opening but not escape.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
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2005年学术文章
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2005年學術文章
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name
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@en
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@nl
type
label
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@en
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@nl
prefLabel
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@en
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@nl
P2093
P2860
P356
P1476
TFIIH XPB mutants suggest a un ...... omoter opening but not escape.
@en
P2093
Jay D Gralla
Wai S Choi
Yin Chun Lin
P2860
P2888
P304
P356
10.1038/NSMB949
P577
2005-06-05T00:00:00Z
P5875
P6179
1000739982