A cell based, high throughput assay for quantitative analysis of Hedgehog pathway activation using a Smoothened activation sensor.

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A cell based, high throughput assay for quantitative analysis of Hedgehog pathway activation using a Smoothened activation sensor.

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2017 nî lūn-bûn

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2017年学术文章

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2017年学术文章

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A cell based, high throughput ...... Smoothened activation sensor.

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A cell based, high throughput ...... Smoothened activation sensor.

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A cell based, high throughput ...... Smoothened activation sensor.

@en

A cell based, high throughput ...... Smoothened activation sensor.

@nl

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A cell based, high throughput ...... Smoothened activation sensor.

@en

A cell based, high throughput ...... Smoothened activation sensor.

@nl

P1476

A cell based, high throughput ...... Smoothened activation sensor.

@en

P2093

Christian Bökel

http://www.w3.org/2001/XMLSchema#string

Evgenii A Albert

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P2860

Small molecule modulation of Smoothened activity

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity

Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

Patched acts catalytically to suppress the activity of Smoothened

Structural basis of Smoothened regulation by its extracellular domains

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromoc

Molecular mechanisms of mTOR-mediated translational control

Specified neural progenitors sort to form sharp domains after noisy Shh signaling.

P2888

s41598-017-14767-1

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14341

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scholarly article

P356

10.1038/S41598-017-14767-1

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English

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P478

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P577

2017-10-30T00:00:00Z

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P6179

1092381619

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P698

29085027

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P932

5662767

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