Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.
about
The role of titin and extracellular matrix remodelling in heart failure with preserved ejection fractionUnderstanding heart failure with preserved ejection fraction: where are we today?Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathyHeart failure with preserved ejection fraction: mechanisms, clinical features, and therapiesHeart failure with preserved ejection fractionThe cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fractionWhat global diastolic function is, what it is not, and how to measure itSarcomeric protein isoform transitions in cardiac muscle: a journey to heart failureProtein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardiumIncreased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in miceWhy does troponin I have so many phosphorylation sites? Fact and fancyImpact of dietary nitrate on age-related diastolic dysfunction.Cardiac myosin binding protein C and MAP-kinase activating death domain-containing gene polymorphisms and diastolic heart failure.Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole.Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffnessWhat we know and do not know about sex and cardiac disease.Heart failure with preserved ejection fraction: molecular pathways of the aging myocardiumPhysiologic basis and pathophysiologic implications of the diastolic properties of the cardiac muscleCalcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient miceDeleting titin's I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function.More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease.Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells.Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatmentContribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.The giant protein titin: a regulatory node that integrates myocyte signaling pathways.Cardiac titin and heart disease.Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodelingProtein changes contributing to right ventricular cardiomyocyte diastolic dysfunction in pulmonary arterial hypertensionDiastolic myofilament dysfunction in the failing human heart.Coronary microvascular rarefaction and myocardial fibrosis in heart failure with preserved ejection fraction.Tachycardia-induced diastolic dysfunction and resting tone in myocardium from patients with a normal ejection fractionTitin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions.Emerging importance of oxidative stress in regulating striated muscle elasticity.Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunctionMyocardial stiffness in patients with heart failure and a preserved ejection fraction: contributions of collagen and titinHeart Failure with Preserved Ejection Fraction: Persistent Diagnosis, Therapeutic Enigma.Cell-to-cell variability in troponin I phosphorylation in a porcine model of pacing-induced heart failure.Attenuated sarcomere lengthening of the aged murine left ventricle observed using two-photon fluorescence microscopyThe multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function.
P2860
Q26765101-97E7C593-57EA-4886-9EA9-F8B9F2FE9BCFQ26766590-75428E10-5D0C-4FDD-90B5-4946D2AB747DQ26799594-BDFB9E94-B3BD-4709-98D5-ADB4B54A6901Q27000263-D24F115E-067C-4DE0-8DD2-0D5C9B333A34Q27024008-CA4C41F7-AC9C-4E25-99E5-5B56C7F6E120Q27024279-E7F13B8D-33F4-46B2-9935-8F9713CEC696Q28087043-7F6A9C7E-7902-4D21-A549-40D9BE4F4115Q28252609-54A05BF3-DF09-41C1-8FF1-6516099E30EEQ28253877-D492CB76-DC79-410F-A999-F4E3DC5A411AQ28263306-6DF744D7-D5C1-4937-84B8-967C62EE7658Q28274412-0C987597-51D1-4C97-A26C-DBC0BB6FC2E8Q30276909-FB1E0DF9-9405-4C89-84F0-DE1FC10B71DEQ31058267-8AD16114-295D-4031-8ECA-78EC84B7FBD1Q33654696-8907AC86-C503-4FF7-82D0-FF69EA23118EQ33787977-EE7AB8A5-37B3-4ED9-A654-D11D28DD722EQ33812503-C109494D-F775-4828-9C2B-DA8A66D5D291Q33889242-66F04106-FCD5-4C37-A75A-54B79A02DD0CQ33961078-C6A5A9FD-6B3D-4E16-9985-BA94AAC0A967Q34049988-D96E8C5B-629C-4DC5-A63A-BC1DB812E74FQ34407578-86DDEB07-A49A-4197-9AF6-FCEBBD63BD93Q34420272-6D8E1B75-3A26-4FCD-AC0F-8D6F939EC9BAQ34439598-A2A0C996-3318-4E2E-A778-83C2D34BDFEFQ34664894-3AAEF3C0-409D-4D76-9EAB-634D02A7627CQ34673137-8CBAFA52-9CB1-49BD-B0DE-BC44A837F945Q34696141-E3DCC39A-22C3-4239-9CBA-83152A86C482Q34721100-B38807E8-E6CC-4249-8325-DB4DB538F8DDQ34995889-BB111316-D577-4E58-B90A-1809ABC6B73BQ35021804-AB57571E-6830-4B5A-A02A-DA572B1A2FBDQ35042592-1FE96415-ECC2-46AC-97F7-0FF80E7F9C54Q35072520-8086580A-39DB-4368-A5A7-DCF820A90810Q35138145-455D62BF-E7B7-43E8-9C1D-DB58E558DFCDQ35147808-9694D12B-3134-4978-BC8F-AFBB3C3A2580Q35155257-B84EA87F-9B93-4281-AD11-8CDBE1B062B5Q35316187-70EE8977-0D46-4294-B174-DAEBB2EA9B67Q35328760-B6747ED6-2D34-4346-817F-BDBB19C9995FQ35536451-E7CB380C-064A-44A7-A77F-DD2AAD25718CQ35898464-5B05463D-0F13-4701-B300-5A08434E770CQ36114325-A4824B26-1B7D-4820-9988-846F4C559643Q36504127-7105A6CA-3146-447F-8841-2692079433FCQ36531058-CC2CC54E-83AF-407A-80DE-F072CB7F2686
P2860
Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@en
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@nl
type
label
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@en
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@nl
prefLabel
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@en
Hypophosphorylation of the Sti ...... n in failing human myocardium.
@nl
P2093
P50
P1433
P1476
Hypophosphorylation of the Sti ...... on in failing human myocardium
@en
P2093
Attila Borbély
István Edes
Jean G F Bronzwaer
Loek van Heerebeek
Nazha Hamdani
Walter J Paulus
Zoltán Papp
P304
P356
10.1161/CIRCRESAHA.108.193326
P577
2009-01-29T00:00:00Z