Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice. - Wikidata - wikimedia - TriplyDB

Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice.

Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice.

http://www.wikidata.org/entity/Q46185789

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FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome Emerging pharmacologic treatment options for fragile X syndrome Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132 Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome Modeling fragile X syndrome in the Fmr1 knockout mouse Fragile X syndrome: mechanistic insights and therapeutic avenues regarding the role of potassium channels.Inhibition of spontaneous recovery of fear by mGluR5 after prolonged extinction training Bidirectional regulation of dendritic voltage-gated potassium channels by the fragile X mental retardation protein Potential therapeutic interventions for fragile X syndrome Activity-dependent regulation of release probability at excitatory hippocampal synapses: a crucial role of fragile X mental retardation protein in neurotransmission Imbalanced pattern completion vs. separation in cognitive disease: network simulations of synaptic pathologies predict a personalized therapeutics strategy.Fragile X targeted pharmacotherapy: lessons learned and future directions.Fragile X syndrome: an update on developing treatment modalities.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Use-dependent AMPA receptor block reveals segregation of spontaneous and evoked glutamatergic neurotransmission Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotype Transient Blockade of ERK Phosphorylation in the Critical Period Causes Autistic Phenotypes as an Adult in Mice Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking fMRP Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome.Synaptic NMDA receptor-mediated currents in anterior piriform cortex are reduced in the adult fragile X mouse Proteomic analysis of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor complexes.The therapeutic potential of insulin-like growth factor-1 in central nervous system disorders.Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome.Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.Role of hippocampal NMDA receptors in a mouse model for fragile X mental retardation syndrome.The role of ionotropic glutamate receptors in childhood neurodevelopmental disorders: autism spectrum disorders and fragile x syndrome.Spatially restricting gene expression by local translation at synapses Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?MicroRNAs in psychiatric and neurodevelopmental disorders.Routes, destinations and delays: recent advances in AMPA receptor trafficking The AMPA receptor as a therapeutic target: current perspectives and emerging possibilities.MicroRNA dysregulation in neuropsychiatric disorders and cognitive dysfunction Testosterone down regulates the expression of Fmr-1 gene in the cerebral cortex of gonadectomized old male mice.Mouse pups lacking collapsin response mediator protein 4 manifest impaired olfactory function and hyperactivity in the olfactory bulb.Pharmacotherapy for Fragile X Syndrome: Progress to Date.Behavioral abnormalities in the Fmr1-KO2 mouse model of fragile X syndrome: The relevance of early life phases.Modelling Autistic Neurons with Induced Pluripotent Stem Cells.

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Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice.

http://www.wikidata.org/entity/Q46185789

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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type

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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The Journal of Physiology

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Synaptic ionotropic glutamate ...... 1 field of Fmr1 knockout mice.

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Aleksander Kolleker

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Andreas Frick

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Ben A Oostra

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Edwin Mientjes

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Melanie Ginger

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Sven Berberich

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Yair Pilpel

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P2860

Genetic enhancement of learning and memory in mice

Correction of fragile X syndrome in mice.

Rho proteins, mental retardation and the cellular basis of cognition

Altered synaptic plasticity in a mouse model of fragile X mental retardation

The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation

Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure

Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits

The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

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787-804

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10.1113/JPHYSIOL.2008.160929

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Pt 4

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587

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Peter H. Seeburg

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2008-12-22T00:00:00Z

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23685290

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19103683

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