Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
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Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain ExchangedTargeting host-derived glycans on enveloped viruses for antibody-based vaccine designEnvelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokinesDefining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds.Rational antibody-based HIV-1 vaccine design: current approaches and future directionsThe glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.MABGEL 1: first phase 1 trial of the anti-HIV-1 monoclonal antibodies 2F5, 4E10 and 2G12 as a vaginal microbicideHow can HIV-type-1-Env immunogenicity be improved to facilitate antibody-based vaccine development?Occluding the mannose moieties on human immunodeficiency virus type 1 gp120 with griffithsin improves the antibody responses to both proteins in mice.2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies.A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.Carbohydrate vaccines: developing sweet solutions to sticky situations?Toward automated oligosaccharide synthesis.Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.Structural principles controlling HIV envelope glycosylation.Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralizationPolysaccharide mimicry of the epitope of the broadly neutralizing anti-HIV antibody, 2G12, induces enhanced antibody responses to self oligomannose glycans.Antibodies expose multiple weaknesses in the glycan shield of HIV.
P2860
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P2860
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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2008年學術文章
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name
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@en
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@nl
type
label
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@en
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@nl
prefLabel
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@en
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens.
@nl
P2093
P1433
P1476
Antigenic mimicry of the HIV envelope by AIDS-associated pathogens
@en
P2093
Ben J Appelmelk
Christopher N Scanlan
D Cameron Dunlop
Dennis R Burton
Nicole Zitzmann
Raymond A Dwek
P304
P356
10.1097/QAD.0B013E328314B5DF
P407
P577
2008-10-01T00:00:00Z