Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. - Wikidata - wikimedia - TriplyDB

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.

http://www.wikidata.org/entity/Q46348775

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Systems biology applied to vaccine and immunotherapy development Controlling NF-kappaB activation in T cells by costimulatory receptors Quantitative analysis by surface plasmon resonance of CD28 interaction with cytoplasmic adaptor molecules Grb2, Gads and p85 PI3K.Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation.Signals and sequences that control CD28 localization to the central region of the immunological synapse.Immunogenomics and systems biology of vaccines.An enigmatic tail of CD28 signaling.Role for the CD28 molecule in the control of Coxiella burnetii infection.Induction of autoimmune disease in CTLA-4-/- mice depends on a specific CD28 motif that is required for in vivo costimulation.Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4 A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant.Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells Functional reprogramming of the primary immune response by T cell receptor antagonism.In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation.Targeted knock-in mice expressing mutations of CD28 reveal an essential pathway for costimulation The Association Between Viral Infections and Co-stimulatory Gene Polymorphisms in Kidney Transplant Outcomes.Systems vaccinology for cancer vaccine development.CD28 Costimulation: From Mechanism to Therapy.Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.Defects in regulatory T cells due to CD28 deficiency induce a qualitative change of allogeneic immune response in chronic graft-versus-host disease.CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.

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P2860

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation.

http://www.wikidata.org/entity/Q46348775

description

2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

@zh-cn

2004年学术文章

@zh-hans

2004年学术文章

@zh-my

2004年学术文章

@zh-sg

2004年學術文章

@yue

2004年學術文章

@zh-hant

name

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@en

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@nl

type

label

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@en

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@nl

prefLabel

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@en

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@nl

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Nature Immunology

P1476

Distinct regions in the CD28 c ...... helper type 2 differentiation.

@en

P2093

Abul K Abbas

http://www.w3.org/2001/XMLSchema#string

Ajay Nirula

http://www.w3.org/2001/XMLSchema#string

Ali Sadra

http://www.w3.org/2001/XMLSchema#string

Douglas Dresnek

http://www.w3.org/2001/XMLSchema#string

John Imboden

http://www.w3.org/2001/XMLSchema#string

Kimberly C Howland

http://www.w3.org/2001/XMLSchema#string

Luke Barron

http://www.w3.org/2001/XMLSchema#string

Pietro G Andres

http://www.w3.org/2001/XMLSchema#string

P2860

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association

The role of Tec protein-tyrosine kinase in T cell signaling

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435-442

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scholarly article

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10.1038/NI1044

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4

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5

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Lawrence P. Kane

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2004-03-07T00:00:00Z

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6283852

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15004555

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