IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.
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HIV: inflammation and bonePrevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptorDiscovery and characterization of olokizumabSpotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to dateTLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.IL-6 receptor antagonist as adjunctive therapy with clotting factor replacement to protect against bleeding-induced arthropathy in hemophiliaPromising bone-related therapeutic targets for rheumatoid arthritis.Bone remodelling markers in rheumatoid arthritis.Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis.Attenuation of collagen-induced arthritis in mice by salmon proteoglycan.IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesityA new strategy to deliver synthetic protein drugs: self-reproducible biologics using minicircles.IL-6 in inflammation, immunity, and diseaseTransglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion.Clinical significance of interleukin (IL)-6 in cancer metastasis to bone: potential of anti-IL-6 therapies.Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine.The roles of interleukin-6 in the pathogenesis of rheumatoid arthritis.Osteoimmunology at the nexus of arthritis, osteoporosis, cancer, and infection.Bone Loss Triggered by the Cytokine Network in Inflammatory Autoimmune Diseases.Tocilizumab for the treatment of rheumatoid arthritis and other systemic autoimmune diseases: current perspectives and future directions.Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis.Bone loss in the HIV-infected patient: evidence, clinical implications, and treatment strategies.A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritisOral squamous carcinoma cells secrete RANKL directly supporting osteolytic bone loss.Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes.Kinetics and interplay of mediators of inflammation-induced bone damage in the course of adjuvant arthritisSarilumab plus methotrexate suppresses circulating biomarkers of bone resorption and synovial damage in patients with rheumatoid arthritis and inadequate response to methotrexate: a biomarker study of MOBILITYRecent advances in neutralizing the IL-6 pathway in arthritis.Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis.Modulatory effect of 1,25-dihydroxyvitamin D 3 on IL1 β -induced RANKL, OPG, TNF α , and IL-6 expression in human rheumatoid synoviocyte MH7A.A novel T cell cytokine, secreted osteoclastogenic factor of activated T cells, induces osteoclast formation in a RANKL-independent manner.Breaking old paradigms: Th17 cells in autoimmune arthritis.Etanercept-Synthesising Mesenchymal Stem Cells Efficiently Ameliorate Collagen-Induced Arthritis.Emerging MRI methods in rheumatoid arthritis.IL-6/IL-6 receptor system and its role in physiological and pathological conditions.Immunotherapeutic implication of IL-6 blockade.Current understanding of rheumatoid arthritis therapy.Tocilizumab for the treatment of systemic juvenile idiopathic arthritis.Can bone loss in rheumatoid arthritis be prevented?Tocilizumab, a humanized anti-IL-6R antibody, as an emerging therapeutic option for rheumatoid arthritis: molecular and cellular mechanistic insights.
P2860
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P2860
IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@en
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@nl
type
label
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@en
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@nl
prefLabel
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@en
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@nl
P2093
P2860
P356
P1433
P1476
IL-6 trans-signalling directly ...... uction by TNF-alpha and IL-17.
@en
P2093
P2860
P304
P356
10.1093/RHEUMATOLOGY/KEN363
P577
2008-09-11T00:00:00Z