Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.
about
Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathwayComplexities of TGF-β targeted cancer therapy.A dynamical systems model for combinatorial cancer therapy enhances oncolytic adenovirus efficacy by MEK-inhibitionThe hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironmentEffect of a chemical inhibitor of human phosphatidylethanolamine-binding protein 4 on radiosensitivity of rectal cancer cellsDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyTargeting the transforming growth factor-beta signaling pathway in human cancer.Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathwayEpithelial to mesenchymal transition in gingival overgrowth.ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progressionCD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination.Human phosphatidylethanolamine-binding protein 4 promoted the radioresistance of human rectal cancer by activating Akt in an ROS-dependent way.ZEB1 limits adenoviral infectability by transcriptionally repressing the coxsackie virus and adenovirus receptor.An epithelial marker promoter induction screen identifies histone deacetylase inhibitors to restore epithelial differentiation and abolishes anchorage independence growth in cancers.Coxsackie and adenovirus receptor (CAR) is a product of Sertoli and germ cells in rat testes which is localized at the Sertoli-Sertoli and Sertoli-germ cell interface.Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasisRole of transforming growth factor-beta in cancer progression.Ocular fibroblast types differ in their mRNA profiles--implications for fibrosis prevention after aqueous shunt implantationNoncanonical TGF-β signaling during mammary tumorigenesis.TGFβ1 inhibition increases the radiosensitivity of breast cancer cells in vitro and promotes tumor control by radiation in vivo.A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transitionPresence of the coxsackievirus and adenovirus receptor (CAR) in human neoplasms: a multitumour array analysisOptimal Control Model of Tumor Treatment with Oncolytic Virus and MEK Inhibitor.Epithelial-mesenchymal transition enhances response to oncolytic herpesviral therapy through nectin-1.Targeting TGF-β Signaling for Therapeutic Gain.Epithelial-mesenchymal transition abolishes the susceptibility of polarized epithelial cell lines to measles virusDownregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1alpha.CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells.RNA interference-mediated knockdown of p21(WAF1) enhances anti-tumor cell activity of oncolytic adenoviruses.The histone deacetylase inhibitors depsipeptide and MS-275, enhance TRAIL gene therapy of LNCaP prostate cancer cells without adverse effects in normal prostate epithelial cells.PDGF enhances IRES-mediated translation of Laminin B1 by cytoplasmic accumulation of La during epithelial to mesenchymal transition.Stromal control of oncogenic traits expressed in response to the overexpression of GLI2, a pleiotropic oncogene.Sodium butyrate increases expression of the coxsackie and adenovirus receptor in colon cancer cells.Expression of the coxsackievirus- and adenovirus receptor in gastrointestinal cancer correlates with tumor differentiation.The protein kinase SIK downregulates the polarity protein Par3.Coxsackievirus and adenovirus receptor-positive cells compose the putative stem/progenitor cell niches in the marginal cell layer and parenchyma of the rat anterior pituitary.
P2860
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P2860
Transforming growth factor-beta receptor inhibition enhances adenoviral infectability of carcinoma cells via up-regulation of Coxsackie and Adenovirus Receptor in conjunction with reversal of epithelial-mesenchymal transition.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Transforming growth factor-bet ...... helial-mesenchymal transition.
@en
Transforming growth factor-bet ...... helial-mesenchymal transition.
@nl
type
label
Transforming growth factor-bet ...... helial-mesenchymal transition.
@en
Transforming growth factor-bet ...... helial-mesenchymal transition.
@nl
prefLabel
Transforming growth factor-bet ...... helial-mesenchymal transition.
@en
Transforming growth factor-bet ...... helial-mesenchymal transition.
@nl
P2093
P1433
P1476
Transforming growth factor-bet ...... thelial-mesenchymal transition
@en
P2093
Allan Balmain
Christine Christian
Elise F Saunier
Markus D Lacher
Martin Oft
Rosemary J Akhurst
Wolfgang Michael Korn
P304
P356
10.1158/0008-5472.CAN-05-2328
P407
P577
2006-02-01T00:00:00Z