Gemfibrozil impairs imatinib absorption and inhibits the CYP2C8-mediated formation of its main metabolite.
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Metabolism-related pharmacokinetic drug-drug interactions with tyrosine kinase inhibitors: current understanding, challenges and recommendations.Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitisPharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 8.Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.Role of gemfibrozil as an inhibitor of CYP2C8 and membrane transporters.Pharmacokinetic drug-drug interactions of tyrosine kinase inhibitors: A focus on cytochrome P450, transporters, and acid suppression therapy.
P2860
Gemfibrozil impairs imatinib absorption and inhibits the CYP2C8-mediated formation of its main metabolite.
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2013 nî lūn-bûn
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2013年の論文
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name
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@en
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@nl
type
label
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@en
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@nl
prefLabel
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@en
Gemfibrozil impairs imatinib a ...... mation of its main metabolite.
@nl
P2860
P50
P356
P1476
Gemfibrozil impairs imatinib a ...... rmation of its main metabolite
@en
P2093
A M Filppula
J T Backman
P2860
P304
P356
10.1038/CLPT.2013.92
P407
P577
2013-05-08T00:00:00Z