The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature. - Wikidata - wikimedia - TriplyDB

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.

http://www.wikidata.org/entity/Q46454014

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Chemokine receptor CXCR2: physiology regulator and neuroinflammation controller?Tumor Necrosis Factor, but Not Neutrophils, Alters the Metabolic Profile in Acute Experimental Arthritis Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis Dual role for Fcγ receptors in host defense and disease in Borrelia burgdorferi-infected mice.Sequence and expression analysis of rainbow trout CXCR2, CXCR3a and CXCR3b aids interpretation of lineage-specific conversion, loss and expansion of these receptors during vertebrate evolution.A self-propagating matrix metalloprotease-9 (MMP-9) dependent cycle of chronic neutrophilic inflammation.The chemokine receptor CXCR2 ligand KC (CXCL1) mediates neutrophil recruitment and is critical for development of experimental Lyme arthritis and carditis.Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model Cooperative role of tumour necrosis factor-α, interleukin-1β and neutrophils in a novel behavioural model that concomitantly demonstrates articular inflammation and hypernociception in mice.Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization Lithothamnion muelleri treatment ameliorates inflammatory and hypernociceptive responses in antigen-induced arthritis in mice.Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration.IRF5 controls both acute and chronic inflammation.Human Lacrimal Gland Gene Expression Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments.CXCR2 Mediates Brucella-Induced Arthritis in Interferon γ-Deficient Mice Macrophage migration inhibitory factor drives neutrophil accumulation by facilitating IL-1β production in a murine model of acute gout.BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.Genetic and Pharmacologic Inhibition of the Chemokine Receptor CXCR2 Prevents Experimental Hypertension and Vascular Dysfunction.A crucial role for TNF-alpha in mediating neutrophil influx induced by endogenously generated or exogenous chemokines, KC/CXCL1 and LIX/CXCL5.In Vitro TNF-α Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of Stryphnodendron adstringens in an Acute Arthritis Model.Role of CXCR2 and TRPV1 in functional, inflammatory and behavioural changes in the rat model of cyclophosphamide-induced haemorrhagic cystitis.The functional significance behind expressing two IL-8 receptor types on PMN.Acute murine antigen-induced arthritis is not affected by disruption of osteoblastic glucocorticoid signalling.The multifactorial role of neutrophils in rheumatoid arthritis.Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review.Myeloid Populations in Systemic Autoimmune Diseases.MicroRNAs in neutrophils: potential next generation therapeutics for inflammatory ailments.G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease.Synovial membrane receptors as therapeutic targets: A review of receptor localization, structure, and function.Myeloperoxidase: A new player in autoimmunity.Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases.Blockade of CXCR1/2 chemokine receptors protects against brain damage in ischemic stroke in mice.Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor.Reparixin attenuates neuronal injury in experimental Klebsiella pneumoniae meningoencephalitis through dual effects on neuroprotection and neuroinflammation.Regulation of early cartilage destruction in inflammatory arthritis by death receptor 3 A homeostatic function of CXCR2 signalling in articular cartilage.Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo.

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The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.

http://www.wikidata.org/entity/Q46454014

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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type

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The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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prefLabel

The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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Arthritis & Rheumatology

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The chemokine receptors CXCR1/ ...... the synovial microvasculature.

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Antônio L Teixeira

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Daniela Sachs

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Daniele G Souza

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David H Rodrigues

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Fernanda M Coelho

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Flávio A Amaral

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Mauro M Teixeira

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Riccardo Bertini

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P2860

Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury

A potent and selective nonpeptide antagonist of CXCR2 inhibits acute and chronic models of arthritis in the rabbit.

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis.

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2329-2337

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scholarly article

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10.1002/ART.23622

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8

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58

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Angélica T Vieira

Tarcilia Aparecida Silva

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2008-08-01T00:00:00Z

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23138894

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18668539

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