PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis. - Wikidata - wikimedia - TriplyDB

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

http://www.wikidata.org/entity/Q51980892

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The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells PKC-Theta in Regulatory and Effector T-cell Functions The Novel PKCθ from Benchtop to Clinic Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ)Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation Automated Quantification of Early Bone Alterations and Pathological Bone Turnover in Experimental Arthritis by in vivo PET/CT Imaging Protective Toxoplasma gondii-specific T-cell responses require T-cell-specific expression of protein kinase C-theta.Protein kinase C θ deficiency increases resistance of C57BL/6J mice to Plasmodium berghei infection-induced cerebral malaria.OX40-OX40L interaction promotes proliferation and activation of lymphocytes via NFATc1 in ApoE-deficient mice.Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?The emerging role of protein kinase Cθ in cytoskeletal signaling.Protein kinase C theta (PKCtheta): a key player in T cell life and death Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation Protein kinase C-theta is required for efficient positive selection.G protein-coupled receptor connectivity to NF-kappaB in inflammation and cancer.PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.The yin and yang of protein kinase C-theta (PKCθ): a novel drug target for selective immunosuppression.PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.PKC-θ function at the immunological synapse: prospects for therapeutic targeting.Protein kinase C and its inhibitors in the regulation of inflammation: inducible nitric oxide synthase as an example.Immune consequences of kinase inhibitors in development, undergoing clinical trials and in current use in melanoma treatment.Selective protein kinase Cθ (PKCθ) inhibitors for the treatment of autoimmune diseases.Targeting PKCθ in skeletal muscle and muscle diseases: good or bad?Duplicity of protein kinase C-θ: Novel insights into human T-cell biology.Ticks produce highly selective chemokine binding proteins with antiinflammatory activity.Intervention of PKC-θ as an immunosuppressive regimen.Protein kinase C-theta is required for development of experimental cerebral malaria.From innate to adaptive immune response in muscular dystrophies and skeletal muscle regeneration: the role of lymphocytes Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential.PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors.Prediction of PKCθ inhibitory activity using the Random Forest Algorithm.MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.Development of Novel Promiscuous Anti-Chemokine Peptibodies for Treating Autoimmunity and Inflammation.The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature.Natural killer cells from protein kinase C theta-/- mice stimulated with interleukin-12 are deficient in production of interferon-gamma.Targeting early PKCθ-dependent T-cell infiltration of dystrophic muscle reduces disease severity in a mouse model of muscular dystrophy.Protein kinase Cθ: the pleiotropic T-cell signalling intermediate.

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PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

http://www.wikidata.org/entity/Q51980892

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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name

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@en

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@nl

type

label

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@en

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@nl

prefLabel

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@en

PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@nl

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JIMMUNOL.177.3.1886

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Journal of Immunology

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PKC-theta-deficient mice are protected from Th1-dependent antigen-induced arthritis.

@en

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Aileen M Healy

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Brett LeClair

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Bruce Jaffee

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Dominic Picarella

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Elena Izmailova

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Elizabeth Siebert

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Jennifer Terkelsen

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Matthew Silva

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Maureen Hattersley

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Michael D Pickard

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1886-1893

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scholarly article

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10.4049/JIMMUNOL.177.3.1886

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3

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2006-08-01T00:00:00Z

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