Synthesis and antitumor activity of novel 4-(2-fluorophenoxy)quinoline derivatives bearing the 4-oxo-1,4-dihydroquinoline-3-carboxamide moiety.

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Design and Synthesis of Novel 4-Phenoxyquinolines Bearing 3-Hydrosulfonylacrylamido or 1H-Imidazole-4-carboxamido Scaffolds as c-Met Kinase Inhibitors.Design, Synthesis, and Biological Evaluation of 4-Phenoxyquinoline Derivatives Containing Benzo[d]thiazole-2-yl Urea as c-Met Kinase Inhibitors.

P2860

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P2860

Synthesis and antitumor activity of novel 4-(2-fluorophenoxy)quinoline derivatives bearing the 4-oxo-1,4-dihydroquinoline-3-carboxamide moiety.

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description

2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年学术文章

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2013年學術文章

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2013年學術文章

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name

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@en

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

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type

Item

label

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@en

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@nl

prefLabel

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@en

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@nl

P1476

Synthesis and antitumor activi ...... uinoline-3-carboxamide moiety.

@en

P2093

Guangyan Zhang

http://www.w3.org/2001/XMLSchema#string

Haicheng Liu

http://www.w3.org/2001/XMLSchema#string

Mingze Qin

http://www.w3.org/2001/XMLSchema#string

Ping Gong

http://www.w3.org/2001/XMLSchema#string

Rui Jiang

http://www.w3.org/2001/XMLSchema#string

Sai Li

http://www.w3.org/2001/XMLSchema#string

P2860

c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations

Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR

Discovery and optimization of triazolopyridazines as potent and selective inhibitors of the c-Met kinase

Design, synthesis, and biological evaluation of potent c-Met inhibitors

Inhibition of tumor cell growth, invasion, and metastasis by EXEL-2880 (XL880, GSK1363089), a novel inhibitor of HGF and VEGF receptor tyrosine kinases

A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients

Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives

Small molecule c-Met kinase inhibitors: a review of recent patents.

Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis.

Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer.

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521-533

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scholarly article

P356

10.1002/ARDP.201300029

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346

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2013-06-17T00:00:00Z

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23776085

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Synthesis and antitumor activity of novel 4-(2-fluorophenoxy)quinoline derivatives bearing the 4-oxo-1,4-dihydroquinoline-3-carboxamide moiety.

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P2860

P2860

Synthesis and antitumor activity of novel 4-(2-fluorophenoxy)quinoline derivatives bearing the 4-oxo-1,4-dihydroquinoline-3-carboxamide moiety.

description

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type

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P1433

P1476

P2093

P2860

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P356

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698