about
Imidazoline RX871024 raises diacylglycerol levels in rat pancreatic islets.Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta.Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose MetabolismRegulation of GPR119 receptor activity with endocannabinoid-like lipids.Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.An endogenous peptide isolated from the gut, NK-lysin, stimulates insulin secretion without changes in cytosolic free Ca2+ concentration.The novel imidazoline compound BL11282 potentiates glucose-induced insulin secretion in pancreatic beta-cells in the absence of modulation of K(ATP) channel activity.Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.Increase in cellular glutamate levels stimulates exocytosis in pancreatic beta-cells.cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells.Ectonucleotidase NTPDase3 is abundant in pancreatic β-cells and regulates glucose-induced insulin secretion.Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells.Activation of prostaglandin E receptor 4 triggers secretion of gut hormone peptides GLP-1, GLP-2, and PYY.A novel glucokinase activator modulates pancreatic islet and hepatocyte function.The PDZ/coiled-coil domain containing protein PIST modulates insulin secretion in MIN6 insulinoma cells by interacting with somatostatin receptor subtype 5.Regulation of Endogenous (Male) Rodent GLP-1 Secretion and Human Islet Insulin Secretion by Antagonism of Somatostatin Receptor 5.GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function.Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells.Different Modes of Action of the Imidazoline Compound RX871024 in Pancreatic beta-Cells: Blocking of K+ Channels, Mobilization of Ca2+ from Endoplasmic Reticulum, and Interaction with Exocytotic MachineryaInsulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-riboseImidazoline compounds stimulate insulin release by inhibition of K(ATP) channels and interaction with the exocytotic machinerySignaling and sites of interaction for RX-871024 and sulfonylurea in the stimulation of insulin releaseEffects of imidazoline derivative RX871024 on insulin, glucagon, and somatostatin secretion from isolated perfused rat pancreasCatechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel
P50
Q32181354-1DEE97CB-8CE0-4031-A479-42D3DC9F81D4Q33900669-8BD29A82-2C7B-4D9A-9F8B-78F5CE20791BQ34982315-8C34A448-C780-4B51-A6EF-46A5B988C2F3Q36056936-9571668C-9F3A-42CE-88E9-F04A7BF77CCCQ39257725-D691CD99-8780-4ED8-90E9-F1010326DEF5Q40239037-51BEFC01-F705-42EA-81A1-9D703FD4E05DQ40286453-AEDCBC63-EFEF-4E97-8BDB-AA1FEECD5947Q40989683-264736A1-8359-46EC-8EEB-07B185BBFF9EQ42502453-49232F5D-B774-4D83-A752-4A0FC1673D47Q44083693-3595B5BB-60CE-4ABD-887C-B6060FF7C223Q44205574-40F9E45B-7EE0-4F4D-B51D-71F4671CDAC2Q44367141-6D261597-D618-4386-BBA1-FF31D7E912BEQ44625507-847AA54A-8412-4AF2-BFD1-A86E905587BDQ45103224-2C70E5C0-4DC0-43A0-987B-9C663899D671Q45161273-94492134-22DB-40E9-B845-C48F84EEFE39Q46101975-0286FB8A-8D04-465F-8CBA-1B4F57F45BAAQ46513192-9C67199B-61CE-4851-B310-8E0AD5E21B37Q46785901-555EE12D-FDC4-4EBD-BBE9-D8D447E6AFCBQ47760798-A4B26EA2-A435-43AD-A220-00FB4385C2AEQ52673362-BAC57998-8A0A-4EAD-A344-663C71D5AFCEQ53580633-DE579F4B-C69C-4E0B-8AC1-A8AFF6099668Q59588561-FB2A8FBB-2E3F-4AC2-8C65-82765948A3E3Q71245673-CF64F308-6191-4559-A448-03A7350D8005Q71674495-0A6B5742-F5D7-4050-952F-473DE17EB2B8Q74518312-0BD4C20C-B22D-47E4-8A6B-A27F4A18C64FQ77545499-6BE4E1D6-4B16-40C8-B862-536AEB968661Q90764379-7311745E-FC85-4AB5-B4B1-FBFEAC5D06CC
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Alexander M Efanov
@ast
Alexander M Efanov
@en
Alexander M Efanov
@es
Alexander M Efanov
@nl
Alexander M Efanov
@sl
type
label
Alexander M Efanov
@ast
Alexander M Efanov
@en
Alexander M Efanov
@es
Alexander M Efanov
@nl
Alexander M Efanov
@sl
prefLabel
Alexander M Efanov
@ast
Alexander M Efanov
@en
Alexander M Efanov
@es
Alexander M Efanov
@nl
Alexander M Efanov
@sl
P1053
N-1416-2016
P106
P21
P31
P3829
P496
0000-0002-8630-1503