Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.
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TRP Channels as Therapeutic Targets in Diabetes and ObesityVoltage gated calcium channels negatively regulate protective immunity to Mycobacterium tuberculosisCaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylationTRPM4 controls insulin secretion in pancreatic beta-cellsDrosophila larval to pupal switch under nutrient stress requires IP3R/Ca(2+) signalling in glutamatergic interneuronsHomodimerization of the Src homology 3 domain of the calcium channel β-subunit drives dynamin-dependent endocytosis.The ß subunit of voltage-gated Ca2+ channelsFacilitation versus depression in cultured hippocampal neurons determined by targeting of Ca2+ channel Cavbeta4 versus Cavbeta2 subunits to synaptic terminalsAblation of Ca2+ channel beta3 subunit leads to enhanced N-methyl-D-aspartate receptor-dependent long term potentiation and improved long term memoryCaV2.3 channel and PKClambda: new players in insulin secretionLoss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- miceShort telomeres compromise β-cell signaling and survival.Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.TRPM5 regulates glucose-stimulated insulin secretion.Transthyretin constitutes a functional component in pancreatic beta-cell stimulus-secretion coupling.Contribution of protein kinase Cα in the stimulation of insulin by the down-regulation of Cavβ subunits.The structural biology of voltage-gated calcium channel function and regulationModerate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.Alone at last! New functions for Ca2+ channel beta subunits?Functional role of TRPC proteins in native systems: implications from knockout and knock-down studies.Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose HomeostasisPhase modulation of insulin pulses enhances glucose regulation and enables inter-islet synchronization.Differential modulation of L-type calcium channel subunits by oleate.Apolipoprotein CIII hyperactivates β cell CaV1 channels through SR-BI/β1 integrin-dependent coactivation of PKA and Src.Structure and function of the β subunit of voltage-gated Ca²⁺ channels.L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.Recent patents on calcium channel blockers: emphasis on CNS diseases.Review: Cav2.3 R-type Voltage-Gated Ca2+ Channels - Functional Implications in Convulsive and Non-convulsive Seizure Activity.Islet amyloid polypeptide acts on glucose- stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca(2+) concentration, and insulin secretion.Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel beta3 subunit.Fasiglifam (TAK-875) has dual potentiating mechanisms via Gαq-GPR40/FFAR1 signaling branches on glucose-dependent insulin secretion.Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents.CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Cytokine-mediated changes in K+ channel activity promotes an adaptive Ca2+ response that sustains β-cell insulin secretion during inflammation.PIP2 in pancreatic β-cells regulates voltage-gated calcium channels by a voltage-independent pathway.
P2860
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P2860
Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@en
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@nl
type
label
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@en
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@nl
prefLabel
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@en
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@nl
P2093
P50
P1433
P1476
Removal of Ca2+ channel beta3 ...... quency and insulin exocytosis.
@en
P2093
Andreas Fernström
Andreas Ludwig
Barbara Leibiger
Christopher J Barker
Claudia Fecher-Trost
Ingo B Leibiger
Ioulia B Appelskog
Jesper Gromada
Lina Moitoso de Vargas
Lisa Juntti-Berggren
P304
P356
10.1016/J.CELL.2004.09.033
P407
P577
2004-10-01T00:00:00Z