Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice.
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Temperature and toxic Tau in Alzheimer's disease: new insightsNMR Meets Tau: Insights into Its Function and PathologyMouse Genetic Models of Human Brain DisordersCritical role of acetylation in tau-mediated neurodegeneration and cognitive deficitsTau physiology and pathomechanisms in frontotemporal lobar degenerationTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseTau StructuresIntrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau FragmentationConserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family MembersAggregation prone regions in human proteome: Insights from large-scale data analyses.Roles of tau protein in health and disease.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Phosphoregulation of Tau modulates inhibition of kinesin-1 motility.Wild-Type, but Not Mutant N296H, Human Tau Restores Aβ-Mediated Inhibition of LTP in Tau-/- mice.Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 micePhosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture.Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling.Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy.Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated KinaseAcetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Glycosylation and other PTMs alterations in neurodegenerative diseases: Current status and future role in neurotrauma.Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.Development of an in-vivo active reversible butyrylcholinesterase inhibitor.Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration.Mass Spectrometry Analysis of Lysine Posttranslational Modifications of Tau Protein from Alzheimer's Disease Brain.Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau's interaction with microtubules in axon-like processes.A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy.Current Understanding of Neurodegenerative Diseases Associated With the Protein Tau.Dual inhibitors of cholinesterases and monoamine oxidases for Alzheimer's disease.The use of human neurons for novel drug discovery in dementia research.Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms.Physiological and Pathophysiological Implications of Synaptic Tau.Cholinergic System and Post-translational Modifications: An Insight on the Role in Alzheimer's DiseaseDetergents: Friends not foes for high-performance membrane proteomics toward precision medicine.Therapeutic strategies for the treatment of tauopathies: Hopes and challenges.Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules.Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins.Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss: Increased levels of acetylated tau blocks the postsynaptic signaling required for plasticity and promotes memory deficits associated with tauopathy.Therapeutic Strategies for Restoring Tau Homeostasis.
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P2860
Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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name
Tau post-translational modific ...... ursor protein transgenic mice.
@en
Tau post-translational modific ...... ursor protein transgenic mice.
@nl
type
label
Tau post-translational modific ...... ursor protein transgenic mice.
@en
Tau post-translational modific ...... ursor protein transgenic mice.
@nl
prefLabel
Tau post-translational modific ...... ursor protein transgenic mice.
@en
Tau post-translational modific ...... ursor protein transgenic mice.
@nl
P2093
P2860
P356
P1433
P1476
Tau post-translational modific ...... ursor protein transgenic mice.
@en
P2093
Alexandra Ioanoviciu
Alma L Burlingame
Giselle M Knudsen
Jonathan C Trinidad
Lennart Mucke
P2860
P2888
P304
P356
10.1038/NN.4067
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P577
2015-07-20T00:00:00Z