Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms.
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α-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson diseaseParkinson's disease: from monogenic forms to genetic susceptibility factorsGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateResearch in Parkinson's disease in India: A review.Genetics of Parkinson's diseaseGenetics in Parkinson disease: Mendelian versus non-Mendelian inheritanceRole of microRNAs in the Regulation of α-Synuclein Expression: A Systematic ReviewMorphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal systemSomatic alpha-synuclein mutations in Parkinson's disease: hypothesis and preliminary data.A 6.4 Mb duplication of the α-synuclein locus causing frontotemporal dementia and Parkinsonism: phenotype-genotype correlations.Copy number variability in Parkinson's disease: assembling the puzzle through a systems biology approachCompounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease modelsLewy Body Dementias: Dementia With Lewy Bodies and Parkinson Disease DementiaMosaicism of alpha-synuclein gene rearrangements: report of two unrelated cases of early-onset parkinsonism.The genetic background of Parkinson's disease: current progress and future prospects.Parkinson's disease and α-synuclein expressionThe genetics of Parkinson's disease: progress and therapeutic implicationsAutosomal dominant Parkinson's disease caused by SNCA duplications.Genetic insights into sporadic Parkinson's disease pathogenesis.The clinical context of copy number variation in the human genome.Exploiting the potential of molecular profiling in Parkinson's disease: current practice and future probabilities.Milestones in PD genetics.Genetic variability in SNCA and Parkinson's disease.Parkinson's disease: from genetics to treatments.The central theme of Parkinson's disease: α-synuclein.Genetic basis of Parkinson's disease: inheritance, penetrance, and expression.Human pluripotent stem cells as tools for neurodegenerative and neurodevelopmental disease modeling and drug discovery.A new role for α-synuclein in Parkinson's disease: Alteration of ER-mitochondrial communication.Review: Parkinson's disease: from synaptic loss to connectome dysfunction.α-Synuclein and Parkinsonism: Updates and Future Perspectives.Endolysosomal dysfunction in Parkinson's disease: Recent developments and future challenges.A53T in a parkinsonian family: a clinical update of the SNCA phenotypes.Subtypes of Parkinson's Disease: What Do They Tell Us About Disease Progression?Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation.Four Copies of SNCA Responsible for Autosomal Dominant Parkinson's Disease in Two Italian Siblings.αSynuclein control of mitochondrial homeostasis in human-derived neurons is disrupted by mutations associated with Parkinson's disease.Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein?EFNS guidelines on the molecular diagnosis of neurogenetic disorders: general issues, Huntington's disease, Parkinson's disease and dystonias.Subthalamic deep brain stimulation for a Parkinson's disease patient with duplication of SNCA.A Clinical and Molecular Genetic Study of 50 Families with Autosomal Recessive Parkinsonism Revealed Known and Novel Gene Mutations.
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P2860
Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@en
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@nl
type
label
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@en
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@nl
altLabel
α-Synuclein Gene Rearrangements in Dominantly Inherited Parkinsonism
@en
prefLabel
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@en
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@nl
P2093
P50
P1433
P1476
Alpha-synuclein gene rearrange ...... cy, phenotype, and mechanisms.
@en
P2093
Alain Destée
Alexandra Dürr
Alexis Brice
Anne-Marie Bonnet
Ebba Lohmann
Frank Durif
Pablo Ibáñez
Sabine Janin
Simon Heath
P304
P356
10.1001/ARCHNEUROL.2008.555
P50
P577
2009-01-01T00:00:00Z