A central segment of the NG2 proteoglycan is critical for the ability of glioma cells to bind and migrate toward type VI collagen.
about
Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent mannerThe multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2The Role of NG2 Proteoglycan in GliomaThe progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling.The NG2 proteoglycan promotes oligodendrocyte progenitor proliferation and developmental myelinationCSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancerChondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycanAstrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation.Collagen VI ablation retards brain tumor progression due to deficits in assembly of the vascular basal lamina.Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration.Recovery from Toxic-Induced Demyelination Does Not Require the NG2 Proteoglycan.Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan.NG2/CSPG4-collagen type VI interplays putatively involved in the microenvironmental control of tumour engraftment and local expansion.Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migrationA role for the NG2 proteoglycan in glioma progression.Recombinant production of proteoglycans and their bioactive domains.Transduction of extracellular cues into cell polarity: the role of the transmembrane proteoglycan NG2.Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse.Roles of NG2-glia in ischemic stroke.The CSPG4-specific monoclonal antibody enhances and prolongs the effects of the BRAF inhibitor in melanoma cells.NG2 proteoglycan mediates beta1 integrin-independent cell adhesion and spreading on collagen VI.Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen).Loss of caveolin-1 causes blood-retinal barrier breakdown, venous enlargement, and mural cell alteration.Shedding of NG2 by MMP-13 attenuates anoikis.Amyloid precursor-like protein 2 promotes cell migration toward fibronectin and collagen IV.NG2 proteoglycan expression in mouse skin: altered postnatal skin development in the NG2 null mouse.Soluble collagen VI drives serum-starved fibroblasts through S phase and prevents apoptosis via down-regulation of Bax.Molecular characterization of cell substratum attachments in human glial tumors relates to prognostic features.Alpha-lipoic acid mitigates toxic-induced demyelination in the corpus callosum by lessening of oxidative stress and stimulation of polydendrocytes proliferation.Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia.Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types.Galectin-3 and galectin-3-binding site expression in human adult astrocytic tumours and related angiogenesis.Effect of mechanical strain on the collagen VI pericellular matrix in anterior cruciate ligament fibroblasts.Gastrin induces over-expression of genes involved in human U373 glioblastoma cell migration.Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma.How do culture media influence in vitro perivascular cell behavior?Abstracts of the XXVII Italian Society for the Study of Connective Tissues (SISC) Meeting, Bologna, Italy, 8-10 November 2007The Significance of Chondroitin Sulfate Proteoglycan 4 (CSPG4) in Human Gliomas
P2860
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P2860
A central segment of the NG2 proteoglycan is critical for the ability of glioma cells to bind and migrate toward type VI collagen.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
A central segment of the NG2 p ...... grate toward type VI collagen.
@en
A central segment of the NG2 p ...... grate toward type VI collagen.
@nl
type
label
A central segment of the NG2 p ...... grate toward type VI collagen.
@en
A central segment of the NG2 p ...... grate toward type VI collagen.
@nl
prefLabel
A central segment of the NG2 p ...... grate toward type VI collagen.
@en
A central segment of the NG2 p ...... grate toward type VI collagen.
@nl
P2093
P356
P1476
A central segment of the NG2 p ...... grate toward type VI collagen.
@en
P2093
P304
P356
10.1006/EXCR.1997.3674
P407
P577
1997-08-01T00:00:00Z