Insights into the human CD59 complement binding interface toward engineering new therapeutics. - Wikidata - wikimedia - TriplyDB

Insights into the human CD59 complement binding interface toward engineering new therapeutics.

Insights into the human CD59 complement binding interface toward engineering new therapeutics.

http://www.wikidata.org/entity/Q46633558

about

High-resolution structures of bacterially expressed soluble human CD59 Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59 Defining the CD59-C9 binding interaction On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9 Regeneration, tissue injury and the immune response.A specific and sensitive assay for blood levels of glycated CD59: a novel biomarker for diabetes.Modulation of protective T cell immunity by complement inhibitor expression on tumor cells.The mammalian complement system as an epitome of host-pathogen genetic conflicts.Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice.Intermedilysin-receptor interactions during assembly of the pore complex: assembly intermediates increase host cell susceptibility to complement-mediated lysis Evolution of cd59 gene in mammals.CD59 inhibits MAC formation

P2860

Q24657819-9D1D2360-7C97-4BE0-B246-1FFE4AAF1303 Q27678091-A259A830-54F6-4F46-A7BF-C70718CC5BAD Q28252317-BECD6631-685D-45EA-B37E-0174FD9F5EC3 Q35037028-6A13938C-858F-4C15-9C5A-E922C96D9799 Q35063359-77A12CDB-ED22-46FC-B19D-A3D28F6E4ED2 Q36605451-AD0C9F12-F468-47F1-A34E-5F70B359D4ED Q37178439-E05A58CF-2E4D-47A3-992F-3A93747F4D6A Q37189831-2FABE286-09C9-457E-A7F2-F4FE962C849A Q40808577-A04D2588-F8B0-472B-A9E3-EA640A276CE7 Q41771843-2E64749F-0228-4158-9BE4-843E250373B5 Q42152568-03C95C96-A3DA-4CB2-A054-D6657379C3FF Q48077209-F5AACC03-6501-4133-B800-21EC9D7B94BF Q50291931-24D65A73-3C78-483D-9D9D-094F9A22F889

P2860

Insights into the human CD59 complement binding interface toward engineering new therapeutics.

http://www.wikidata.org/entity/Q46633558

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh-hant

name

Insights into the human CD59 c ...... engineering new therapeutics.

@en

Insights into the human CD59 c ...... engineering new therapeutics.

@nl

type

label

Insights into the human CD59 c ...... engineering new therapeutics.

@en

Insights into the human CD59 c ...... engineering new therapeutics.

@nl

prefLabel

Insights into the human CD59 c ...... engineering new therapeutics.

@en

Insights into the human CD59 c ...... engineering new therapeutics.

@nl

P1433

Q46633558-937914B1-EE19-4686-BBBE-C45DC1475158

P1476

Q46633558-66535BA5-64CE-4457-96AE-4427C057E0CF

P2093

Q46633558-414D594F-E6D1-48AD-B826-1FCA58B63AF6

Q46633558-59A836B9-B54C-45E3-B5EF-F0113860F6E8

Q46633558-8C9C3A43-13B0-4825-8BF3-40AA0636BDB9

Q46633558-BC2915D1-8DAA-42EE-8F28-86647B86BD88

Q46633558-C0ECEB13-E690-45CA-A7EA-E9CA6803B14D

Q46633558-F36F0965-E42A-4E17-95BA-912CEFA37510

P2860

Q46633558-014008B7-264B-4F00-A29E-18CC2280E410

Q46633558-2C8FB04C-82C5-4E15-ADBD-2E8E554791D9

Q46633558-3E380CAA-BDD3-4071-A97A-C283081E26A0

Q46633558-44211231-7EEB-4455-B407-130F7308558D

Q46633558-4A1692F1-72A9-4A2F-84B4-2F70D7135456

Q46633558-561407A9-D97F-47D8-BF7C-0AFFCE5A1489

Q46633558-56AE1992-743E-4E4F-84B0-7FF00AE35C7F

Q46633558-62CA9158-F848-4D2D-997F-0BF2AED860AF

Q46633558-66972A8A-72CA-4A7F-A5F0-099B9D35C491

Q46633558-6765A509-35E3-4943-8821-8F54822AE277

P304

Q46633558-8DEE1991-4B43-4701-9CB1-18E768075AA5

P31

Q46633558-5A7BAB15-F670-438B-8E15-45D8A6F3CB74

P356

Q46633558-41A3AC82-1D4B-4302-8B5F-31D3DD7EC4F1

P407

Q46633558-0104EAD8-E85F-467A-BEC4-39B6B2758B43

P433

Q46633558-8B3A297B-8D3C-44B3-8046-B7AD6342483A

P478

Q46633558-6A5A905D-0447-4168-8F02-89269D8D56ED

P577

Q46633558-E3329F57-D3B8-44ED-92B0-FD77C798D0A6

P698

Q46633558-28AF73B9-7603-4CBA-B4A8-3EE049ACEE42

P356

P1433

Journal of Biological Chemistry

P1476

Insights into the human CD59 c ...... engineering new therapeutics.

@en

P2093

B Paul Morgan

http://www.w3.org/2001/XMLSchema#string

Colin A Smith

http://www.w3.org/2001/XMLSchema#string

Hongbin Song

http://www.w3.org/2001/XMLSchema#string

Ruben Abagyan

http://www.w3.org/2001/XMLSchema#string

Stephen Tomlinson

http://www.w3.org/2001/XMLSchema#string

Yuxiang Huang

http://www.w3.org/2001/XMLSchema#string

P2860

Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity

Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59

Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins.

Targeting of functional antibody-CD59 fusion proteins to a cell surface.

Complement inhibitors: a resurgent concept in anti-inflammatory therapeutics.

Identity of the segment of human complement C8 recognized by complement regulatory protein CD59.

Complement function in mAb-mediated cancer immunotherapy.

The role of the complement system in ischemia-reperfusion injury.

P304

34073-34079

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M504922200

http://www.w3.org/2001/XMLSchema#string

P407

P433

40

http://www.w3.org/2001/XMLSchema#string

P478

280

http://www.w3.org/2001/XMLSchema#string

P577

2005-08-03T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16079145

http://www.w3.org/2001/XMLSchema#string