Mutations in the B2 bradykinin receptor reveal a different pattern of contacts for peptidic agonists and peptidic antagonists.

Mutations in the B2 bradykinin receptor reveal a different pattern of contacts for peptidic agonists and peptidic antagonists.

Item
http://www.wikidata.org/entity/Q46682973
Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundleIn various tumour cell lines the peptide bradykinin B(2) receptor antagonist, Hoe 140 (Icatibant), may act as mitogenic agonistThe importance of the N-terminal beta-turn in bradykinin antagonists.Molecular basis of ligand dissociation in β-adrenergic receptorsAgonist binding by the β2-adrenergic receptor: an effect of receptor conformation on ligand association-dissociation characteristicsIcatibant , the bradykinin B2 receptor antagonist with target to the interconnected kinin systems.Pharmacological characterization of ligand-receptor interactions at the zebrafish bradykinin receptor.Identification of ligand effector binding sites in transmembrane regions of the human G protein-coupled C3a receptor.Motif mutation of bradykinin B2 receptor second intracellular loop and proximal C terminus is critical for signal transduction, internalization, and resensitization.Pharmacological characterization of canine bradykinin receptors in prostatic culture and in isolated prostate.Comparison of the molecular interactions of two antagonists, MEN16132 or icatibant, at the human kinin B₂ receptor.A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B2 receptor: evidence from mutational analysis.Control of conformational equilibria in the human B2 bradykinin receptor. Modeling of nonpeptidic ligand action and comparison to the rhodopsin structure.Preliminary mutational analysis of the human kinin B2 receptor for nonpeptide antagonist ligands recognition.Changes in amino-terminal portion of human B2 receptor selectively increase efficacy of synthetic ligand HOE 140 but not of cognate ligand bradykinin.Monomeric monocyte chemoattractant protein-1 (MCP-1) binds and activates the MCP-1 receptor CCR2B.The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors.
P2860

Mutations in the B2 bradykinin receptor reveal a different pattern of contacts for peptidic agonists and peptidic antagonists.

Item
http://www.wikidata.org/entity/Q46682973
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@en
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@nl
type
label
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@en
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@nl
prefLabel
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@en
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P356
P1433
P1476
Mutations in the B2 bradykinin ...... ists and peptidic antagonists.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698