The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.
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Regulation of T Cell Differentiation and Function by EZH2Post-translational modification-regulated leukocyte adhesion and migrationNeutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.Cellular and molecular regulation of innate inflammatory responsesFocal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2.Interleukin-10 reorganizes the cytoskeleton of mature dendritic cells leading to their impaired biophysical properties and motilitiesGSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.The JAZF1-SUZ12 fusion protein disrupts PRC2 complexes and impairs chromatin repression during human endometrial stromal tumorogenesisInside the Cell: Integrins as New Governors of Nuclear Alterations?Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase.A non-canonical function of Ezh2 preserves immune homeostasis.TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.Epigenetic regulation of cancer biology and anti-tumor immunity by EZH2.Dendritic cell migration in health and disease.Structure of the PRC2 complex and application to drug discovery.Emerging Role for Methylation in Multiple Sclerosis: Beyond DNA.Polycomb Repressive Complex 2-Mediated Chromatin Repression Guides Effector CD8+ T Cell Terminal Differentiation and Loss of Multipotency.One crisis, diverse impacts-Tissue-specificity of folate deficiency-induced circulation defects in zebrafish larvae.The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3.EZH2 promotes neoplastic transformation through VAV interaction-dependent extranuclear mechanisms.EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion Through Junctional Adhesion Molecule A in Lupus Patients.A cytosolic Ezh1 isoform modulates a PRC2-Ezh1 epigenetic adaptive response in postmitotic cells.Enhancer of zeste homolog 2 promotes cisplatin resistance by reducing cellular platinum accumulation.Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential.Isolation and Activation of Murine Lymphocytes.Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects.p38-mediated phosphorylation at T367 induces EZH2 cytoplasmic localization to promote breast cancer metastasisCirculating EZH2-positive T cells are decreased in multiple sclerosis patientsPolycomb Repressive Complex 2 is essential for development and maintenance of a functional TEC compartment
P2860
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P2860
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@en
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@nl
type
label
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@en
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@nl
prefLabel
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@en
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@nl
P2093
P2860
P50
P356
P1433
P1476
The methyltransferase Ezh2 con ...... lear regulatory protein talin.
@en
P2093
Heidi Berger
Jia Tong Loh
Keh Chuang Chin
Merry Gunawan
Myint Khun La Win
Nandini Venkatesan
Sayuri Yamazaki
Susana Geifman Shochat
P2860
P2888
P304
P356
10.1038/NI.3125
P407
P50
P577
2015-03-09T00:00:00Z
P5875
P6179
1042763785